There are 7 ways to get from Istres to Lyon by train (TGV, Trenitalia), bus, car, train, plane, or rideshare
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Avignon
best- Take the train from Miramas to Avignon Centretrain Ter
- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
3h 11m€41–100Rideshare
cheapest- Take the rideshare from Istres to Lyon284.3 km
3h 18m€15–21Bus
- Take the bus from Aix-en-Provence - Krypton Park & Ride to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
6h 33m€26–50Drive 282.4 km
- Drive from Istres to Lyoncar 282.4 km
2h 51m€46–66Train, fly
- Take the train from Istres to Miramastrain
- Take the train from Miramas to Vitrolles Aeroport Marseilletrain
- Fly from Marseille Provence Airport (MRS) to Lyon–Saint Exupéry Airport (LYS)plane MRS - LYS
3h 28m€105–283Train
- Take the train from Miramas to Lyon Part Dieutrain Ter
4h 29m€51–111Train via Livron-sur-Drôme
- Take the train from Miramas to Livrontrain K34
- Take the train from Livron to Lyon Jean Macétrain K24
5h 37m€76–111
Istres to Lyon by train
Comparing Your Travel Options
The cheapest way to get from Istres to Lyon is to rideshare which costs €15 - €21 and takes 3h 18m.
The fastest way to get from Istres to Lyon is to drive which takes 2h 51m and costs €45 - €70.
No, there is no direct bus from Istres to Lyon station. However, there are services departing from Les Carmes and arriving at Lyon - Gerland Bus Station via Gare Routière and Aix-en-Provence - Krypton Park & Ride. The journey, including transfers, takes approximately 6h 33m.
No, there is no direct train from Istres to Lyon. However, there are services departing from Istres and arriving at Lyon Part Dieu via Miramas, Avignon Centre and Avignon Tgv. The journey, including transfers, takes approximately 3h 11m.
The distance between Istres and Lyon is 310 km. The road distance is 282.4 km.
The best way to get from Istres to Lyon without a car is to train via Avignon which takes 3h 11m and costs €40 - €100.
It takes approximately 3h 11m to get from Istres to Lyon, including transfers.
Istres to Lyon bus services, operated by BlaBlaCar Bus, depart from Aix-en-Provence - Krypton Park & Ride station.
Istres to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Miramas station.
The best way to get from Istres to Lyon is to train via Avignon which takes 3h 11m and costs €40 - €100. Alternatively, you can bus, which costs €26 - €50 and takes 6h 33m.
What companies run services between Istres, France and Lyon, France?
You can take a train from Istres to Lyon Part Dieu via Miramas, Avignon Centre, and Avignon Tgv in around 3h 11m. Alternatively, BlaBlaCar Bus operates a bus from Aix-en-Provence - Krypton Park & Ride to Lyon - Gerland Bus Station every 2 hours. Tickets cost €19–35 and the journey takes 4h. FlixBus also services this route 3 times a day.
- Website
- airfrance.com
Flights from Marseille Provence Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 55 min
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €35–280
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Miramas to Avignon Centre
- Ave. Duration
- 1h 10m
- Frequency
- Every 30 minutes
- Estimated price
- €11–21
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 3 times a day
- Estimated price
- €35–70
- Website
- Oui.SNCF
Train from Istres to Miramas
- Ave. Duration
- 9 min
- Frequency
- Hourly
- Estimated price
- €1–4
- Website
- Oui.SNCF
Train from Miramas to Vitrolles Aeroport Marseille
- Ave. Duration
- 21 min
- Frequency
- Every 20 minutes
- Estimated price
- €5–9
- Website
- Oui.SNCF
Train from Miramas to Lyon Part Dieu
- Ave. Duration
- 3h 13m
- Frequency
- Every 4 hours
- Estimated price
- €50–90
- Website
- Oui.SNCF
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Aix-en-Provence - Krypton Park & Ride to Lyon - Gerland Bus Station
- Ave. Duration
- 4h
- Frequency
- Every 2 hours
- Estimated price
- €19–35
- Website
- BlaBlaCar Bus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Istres to Lyon
- Ave. Duration
- 3h 18m
- Frequency
- Once daily
- Estimated price
- €15–21
- Schedules at
- BlaBlaCar
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Istres to Lyon bus services, operated by BlaBlaCar Bus, arrive at Lyon - Gerland Bus Station.
Istres to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Avignon Centre station.
Yes, the driving distance between Istres to Lyon is 282 km. It takes approximately 2h 51m to drive from Istres to Lyon.
Book your Istres to Lyon train tickets online with Omio.
There are 3925+ hotels available in Lyon.
Check out Blablacar's carpooling service for rideshare options between Istres and Lyon. A great option if you don't have a driver's licence or want to avoid public transport.












