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How to get fromIthaca to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 11 ways to get from Ithaca to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ithaca Tompkins Regional Airport to Mcghee Tyson Airport, drive

    best
    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Mcghee Tyson Airport (TYS)plane plane ITH - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 26m
    $140–683

  2. Fly Ithaca Tompkins Regional Airport to Greenville–Spartanburg International Airport, drive

    cheapest
    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Greenville–Spartanburg International Airport (GSP)plane plane ITH - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    8h 34m
    $129–582

  3. Bus, drive

    1. Take the bus from Ithaca to New York Midtownbus bus
    2. Take the bus from New York to Knoxvillebus bus Nyc
    3. Drive from Knoxville to Great Smoky Mountainscar car
    19h 42m
    $149–226

  4. Bus, train, drive

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Albany-Rensselaer Amtrak Stationtrain train
    3. Take the train from Albany-Rensselaer Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    26h
    $294–712

  5. Drive 734.9 mi

    1. Drive from Ithaca to Great Smoky Mountainscar car 734.9 mi
    14h 9m
    $135–194

  6. Bus to Greater Binghamton Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Ithaca to Binghamtonbus bus
    2. Fly from Greater Binghamton Airport (BGM) to Mcghee Tyson Airport (TYS)plane plane BGM - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 26m
    $193–824

  7. Bus to Elmira/Corning Regional Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus bus
    2. Fly from Elmira/Corning Regional Airport (ELM) to Mcghee Tyson Airport (TYS)plane plane ELM - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 27m
    $156–774

  8. Bus to Syracuse Hancock International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Mcghee Tyson Airport (TYS)plane plane SYR - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 25m
    $203–1,010

  9. Bus, drive via Farragut

    1. Take the bus from Ithaca to New York Midtownbus bus
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Great Smoky Mountainscar car
    19h 49m
    $148–194

  10. Bus, drive via Farragut #2

    1. Take the bus from Ithaca, NY to New York, NYbus bus
    2. Take the bus from Willow Ave At 15Th St to Port Authority Bus Terminalbus bus 126 / ...
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    4. Drive from Knoxville, TN to Great Smoky Mountainscar car
    19h 57m
    $187–312

  11. Bus, drive via Farragut #3

    1. Take the bus from Ithaca to Port Authority Bus Terminalbus bus 231
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Great Smoky Mountainscar car
    20h 11m
    $147–270

Ithaca Tompkins Regional Airport (ITH) to Mcghee Tyson Airport (TYS) flights

Calendar32Weekly Planes
Duration5h 5mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Ithaca to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 679.7 mi
  • Duration: 7h 26m

What companies run services between Ithaca, NY, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Ithaca to Great Smoky Mountains. However, you can take the line 32 bus to Airport, walk to Ithaca Tompkins Regional Airport (ITH) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Ithaca to Great Smoky Mountains via New York Midtown, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 19h 42m.

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