There are 8 ways to get from Ithaca to Key West by plane, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Ithaca Tompkins Regional Airport
best- Fly from Ithaca Tompkins Regional Airport (ITH) to Key West International Airport (EYW)plane ITH - EYW
7h 51m$97–414Bus
- Take the bus from Ithaca to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
37h 41m$258–399Bus, train
- Take the bus from Ithaca to Newark Penn Stationbus
- Take the train from Newark Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
40h 31m$827–1,313Drive 1,503.5 mi
- Drive from Ithaca to Key Westcar 1,503.5 mi
27h 13m$275–397Bus to Rochester, fly
- Take the bus from Ithaca to Rochester, Nybus
- Fly from Rochester (ROC) to Key West International Airport (EYW)plane ROC - EYW
7h 59m$171–690Bus to Syracuse Hancock International Airport, fly
- Take the bus from Ithaca to Syracuse Bus Stationbus
- Fly from Syracuse Hancock International Airport (SYR) to Key West International Airport (EYW)plane SYR - EYW
8h 35m$154–654Bus to Newark Liberty International Airport, fly
- Take the bus from Ithaca to Newark Penn Stationbus
- Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)plane EWR - EYW
9h 17m$149–519Bus to Laguardia Airport, fly
- Take the bus from Ithaca to New York Midtownbus
- Fly from Laguardia Airport (LGA) to Key West International Airport (EYW)plane LGA - EYW
10h 27m$166–635
Ithaca to Key West by bus and foot
Comparing Your Travel Options
The cheapest way to get from Ithaca to Key West is to fly which costs $95 - $420 and takes 7h 51m.
The fastest way to get from Ithaca to Key West is to fly which takes 7h 51m and costs $95 - $420.
No, there is no direct bus from Ithaca to Key West. However, there are services departing from Ithaca and arriving at N Roosevelt & 3rd Street via Newark Penn Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 37h 41m.
The distance between Ithaca and Key West is 1293 miles. The road distance is 1512.2 miles.
The best way to get from Ithaca to Key West without a car is to bus which takes 37h 41m and costs $250 - $400.
It takes approximately 7h 51m to get from Ithaca to Key West, including transfers.
Ithaca to Key West bus services, operated by Flixbus USA, depart from Ithaca station.
The best way to get from Ithaca to Key West is to fly which takes 7h 51m and costs $95 - $420. Alternatively, you can bus, which costs $250 - $400 and takes 37h 41m.
Ithaca to Key West bus services, operated by Flixbus USA, arrive at Newark Penn Station.
Yes, the driving distance between Ithaca to Key West is 1512 miles. It takes approximately 27h 13m to drive from Ithaca to Key West.
What companies run services between Ithaca, NY, USA and Key West, FL, USA?
United Airlines flies from Ithaca Tompkins Regional Airport (ITH) to Key West International Airport (EYW) once daily. Alternatively, you can take a bus from Ithaca to N Roosevelt & 3rd Street via Newark Penn Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 37h 41m.
- Website
- aa.com
Flights from Rochester to Key West International Airport via Miami
- Ave. Duration
- 5h 43m
- When
- Saturday
- Estimated price
- $120–600
Flights from Rochester to Key West International Airport via Charlotte
- Ave. Duration
- 5h 59m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Rochester to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $120–600
Flights from Syracuse Hancock International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–600
Flights from Syracuse Hancock International Airport to Key West International Airport via Miami
- Ave. Duration
- 8h 3m
- When
- Saturday
- Estimated price
- $130–600
Flights from Newark Liberty International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $90–430
Flights from Laguardia Airport to Key West International Airport
- Ave. Duration
- 3h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Laguardia Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 29m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Rochester to Key West International Airport via Atlanta
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $120–600
Flights from Syracuse Hancock International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $130–650
Flights from Newark Liberty International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–460
Flights from Laguardia Airport to Key West International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $110–550
Flights from Laguardia Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $130–600
- Website
- united.com
Flights from Ithaca Tompkins Regional Airport to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $85–410
Flights from Rochester to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Newark Liberty International Airport to Key West International Airport
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- $85–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Newark Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 6m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Ithaca to Newark Penn Station
- Ave. Duration
- 4h 20m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Miami Airport Station
- Ave. Duration
- 25h 25m
- Frequency
- 4 times a week
- Estimated price
- $200–310
- Schedules at
- Flixbus USA
Bus from Ithaca to Newark Penn Station
- Ave. Duration
- 4h 20m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Ithaca to Newark Penn Station
- Ave. Duration
- 4h 20m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Ithaca to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- 4 times a day
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 965+ hotels available in Key West.








