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How to get fromIthaca to Louisvilleby plane, bus, train, car, or bus (Flixbus, Greyhound, Amtrak)

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There are 11 ways to get from Ithaca to Louisville by plane, bus, train, car, or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Ithaca Tompkins Regional Airport

    best
    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Louisville International Airport (SDF)plane plane ITH - SDF
    6h 53m
    $126–678

  2. Bus to Elmira/Corning Regional Airport, fly

    cheapest
    1. Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus bus
    2. Fly from Elmira/Corning Regional Airport (ELM) to Louisville International Airport (SDF)plane plane ELM - SDF
    8h 25m
    $117–711

  3. Bus, train via Toledo

    1. Take the bus from Ithaca to Rochester, Nybus bus 246
    2. Take the train from Rochester to Toledotrain train
    3. Take the bus from Toledo to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    17h 34m
    $254–474

  4. Bus, train

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 11m
    $491–829

  5. Drive  656.9 mi

    1. Drive from Ithaca to Louisvillecar car 656.9 mi
    11h 39m
    $120–174

  6. Bus to Rochester, fly

    1. Take the bus from Ithaca to Rochester, Nybus bus
    2. Fly from Rochester (ROC) to Louisville International Airport (SDF)plane plane ROC - SDF
    8h
    $201–1,030

  7. Bus to Greater Binghamton Airport, fly

    1. Take the bus from Ithaca to Binghamtonbus bus
    2. Fly from Greater Binghamton Airport (BGM) to Louisville International Airport (SDF)plane plane BGM - SDF
    10h 33m
    $163–759

  8. Bus to Syracuse Hancock International Airport, fly

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Louisville International Airport (SDF)plane plane SYR - SDF
    8h 51m
    $193–1,044

  9. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Ithaca to Newark Penn Stationbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    9h 11m
    $172–827

  10. Bus

    1. Take the bus from Ithaca to Buffalobus bus
    2. Take the bus from Buffalo to Columbusbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    19h 37m
    $129–210

  11. Bus, train #2

    1. Take the bus from Ithaca to Newark Penn Stationbus bus
    2. Take the train from Newark Penn Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    31h 8m
    $554–893

Ithaca to Louisville by bus and train

Calendar7Weekly Services
Duration17h 34mAverage Duration
Ticket$254Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ithaca to Louisville.ExpandLaunch map view
  • Distance: 585.2 mi
  • Duration: 6h 53m

What companies run services between Ithaca, NY, USA and Louisville, KY, USA?

United Airlines flies from Ithaca Tompkins Regional Airport (ITH) to Louisville International Airport (SDF) 4 times a day. Alternatively, you can take a bus from Ithaca to Louisville, KY via Buffalo, Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, and Indianapolis Union Station in around 19h 37m.

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