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How to get fromIthaca to Mayo Clinicby bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Flixbus)

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There are 11 ways to get from Ithaca to Mayo Clinic by bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Rochester, fly to Rochester

    best
    1. Take the bus from Ithaca to Rochester, Nybus bus
    2. Fly from Rochester (ROC) to Rochester (RST)plane plane ROC - RST
    8h 52m
    $154–648

  2. Bus to Syracuse Hancock International Airport, fly to Rochester

    cheapest
    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Rochester (RST)plane plane SYR - RST
    9h 33m
    $137–664

  3. Bus, train via Madison

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    25h 11m
    $295–586

  4. Bus

    1. Take the bus from Ithaca to Buffalobus bus
    2. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    5. Take the bus from Milwaukee to Rochesterbus bus
    26h 15m
    $193–419

  5. Drive 1,003.2 mi

    1. Drive from Ithaca to Mayo Cliniccar car 1,003.2 mi
    17h 24m
    $184–265

  6. Fly Ithaca Tompkins Regional Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Minneapolis–Saint Paul International Airport (MSP)plane plane ITH - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 20m
    $184–635

  7. Bus to Syracuse Hancock International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Minneapolis–Saint Paul International Airport (MSP)plane plane SYR - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 57m
    $205–795

  8. Bus to Buffalo Niagara International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Ithaca to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Minneapolis–Saint Paul International Airport (MSP)plane plane BUF - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 23m
    $210–843

  9. Bus to Elmira/Corning Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus bus
    2. Fly from Elmira/Corning Regional Airport (ELM) to Minneapolis–Saint Paul International Airport (MSP)plane plane ELM - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    11h
    $158–610

  10. Bus, train

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochester, MNbus bus
    26h 36m
    $378–766

  11. Bus via Detroit

    1. Take the bus from Ithaca to Torontobus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    30h 38m
    $231–453

Ithaca to Mayo Clinic by bus, train, and foot

Calendar8Weekly Services
Duration26h 36mAverage Duration
Ticket$378Cheapest Price
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Questions & Answers

Map of how to get from Ithaca to Mayo Clinic.ExpandLaunch map view
  • Distance: 849.3 mi
  • Duration: 8h 52m

What companies run services between Ithaca, NY, USA and Mayo Clinic, MN, USA?

You can take a bus from Ithaca to Mayo Clinic via Buffalo, Cleveland Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 26h 15m.

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Train operators
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