There are 11 ways to get from Ithaca to Mayo Clinic by bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Rochester, fly to Rochester
best- Take the bus from Ithaca to Rochester, Nybus
- Fly from Rochester (ROC) to Rochester (RST)plane ROC - RST
9h 39m$151–717Bus to Syracuse Hancock International Airport, fly to Rochester
cheapest- Take the bus from Ithaca to Syracuse Bus Stationbus
- Fly from Syracuse Hancock International Airport (SYR) to Rochester (RST)plane SYR - RST
11h 14m$94–512Bus, train via Madison
- Take the bus from Ithaca to Syracuse Bus Stationbus
- Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
25h 6m$445–745Bus
- Take the bus from Ithaca to Buffalobus
- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Rochesterbus
25h 56m$206–313Drive 1,003.2 mi
- Drive from Ithaca to Mayo Cliniccar 1,003.2 mi
17h 21m$166–240Bus to Buffalo Niagara International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Ithaca to Buffalobus
- Fly from Buffalo Niagara International Airport (BUF) to Minneapolis–Saint Paul International Airport (MSP)plane BUF - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
9h 55m$160–567Fly Ithaca Tompkins Regional Airport to Minneapolis–Saint Paul International Airport, bus
- Fly from Ithaca Tompkins Regional Airport (ITH) to Minneapolis–Saint Paul International Airport (MSP)plane ITH - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
9h 40m$176–651Bus to Syracuse Hancock International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Ithaca to Syracuse Bus Stationbus
- Fly from Syracuse Hancock International Airport (SYR) to Minneapolis–Saint Paul International Airport (MSP)plane SYR - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
9h 32m$163–642Bus to Elmira/Corning Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus
- Fly from Elmira/Corning Regional Airport (ELM) to Minneapolis–Saint Paul International Airport (MSP)plane ELM - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
11h 13m$156–608Bus, train
- Take the bus from Ithaca to Syracuse Bus Stationbus
- Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
26h 24m$618–1,005Bus via Detroit
- Take the bus from Ithaca to Torontobus
- Take the bus from Toronto to Detroit Bus Stationbus
- Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Rochesterbus
31h 1m$203–313
Ithaca to Mayo Clinic by bus, train, and foot
Comparing Your Travel Options
The cheapest way to get from Ithaca to Mayo Clinic is to drive which costs $160 - $240 and takes 17h 21m.
The fastest way to get from Ithaca to Mayo Clinic is to bus and fly which takes 9h 32m and costs $160 - $650.
No, there is no direct bus from Ithaca to Mayo Clinic. However, there are services departing from Ithaca and arriving at Rochester via Buffalo, Cleveland Bus Station, Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 25h 56m.
The distance between Ithaca and Mayo Clinic is 854 miles. The road distance is 1009.1 miles.
The best way to get from Ithaca to Mayo Clinic without a car is to bus and train via Madison which takes 25h 6m and costs $440 - $750.
It takes approximately 9h 39m to get from Ithaca to Mayo Clinic, including transfers.
Ithaca to Mayo Clinic bus services, operated by Trailways, depart from Ithaca station.
Ithaca to Mayo Clinic bus services, operated by Trailways, arrive at Buffalo station.
Yes, the driving distance between Ithaca to Mayo Clinic is 1009 miles. It takes approximately 17h 21m to drive from Ithaca to Mayo Clinic.
There are 76+ hotels available in Mayo Clinic.
What companies run services between Ithaca, NY, USA and Mayo Clinic, MN, USA?
You can take a bus from Ithaca to Mayo Clinic via Buffalo, Cleveland Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 25h 56m.
- Website
- delta.com
Flights from Rochester to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $120–650
Flights from Syracuse Hancock International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 8h 50m
- When
- Every day
- Estimated price
- $85–440
Flights from Syracuse Hancock International Airport to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $85–450
Flights from Syracuse Hancock International Airport to Rochester via New York La Guardia, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 11h 2m
- When
- Every day
- Estimated price
- $100–500
Flights from Buffalo Niagara International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $85–480
Flights from Ithaca Tompkins Regional Airport to Minneapolis–Saint Paul International Airport via New York JFK
- Ave. Duration
- 9h 4m
- When
- Every day
- Estimated price
- $130–650
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 52m
- When
- Every day
- Estimated price
- $100–550
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $100–550
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport via New York La Guardia
- Ave. Duration
- 6h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Elmira/Corning Regional Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $100–550
Flights from Elmira/Corning Regional Airport to Minneapolis–Saint Paul International Airport via Detroit, Madison
- Ave. Duration
- 7h 44m
- When
- Every day
- Estimated price
- $100–550
Flights from Elmira/Corning Regional Airport to Minneapolis–Saint Paul International Airport via Detroit, Milwaukee
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $100–550
Flights from Elmira/Corning Regional Airport to Minneapolis–Saint Paul International Airport via Detroit, Traverse City
- Ave. Duration
- 8h 48m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Rochester to Rochester via Chicago O'Hare
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $110–600
Flights from Syracuse Hancock International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $80–430
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $110–550
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport via Reagan Washington
- Ave. Duration
- 5h 37m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $130–650
- Website
- united.com
Flights from Buffalo Niagara International Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $90–490
Flights from Ithaca Tompkins Regional Airport to Minneapolis–Saint Paul International Airport via Washington Dulles
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $120–600
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $110–550
Flights from Syracuse Hancock International Airport to Minneapolis–Saint Paul International Airport via Washington Dulles
- Ave. Duration
- 5h 29m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $95–500
Flights from Buffalo Niagara International Airport to Minneapolis–Saint Paul International Airport via Baltimore
- Ave. Duration
- 4h 55m
- When
- Monday and Thursday
- Estimated price
- $120–600
- Website
- suncountry.com
Flights from Ithaca Tompkins Regional Airport to Minneapolis–Saint Paul International Airport via Washington Dulles
- Ave. Duration
- 4h 52m
- When
- Thursday
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $360–600
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $360–600
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Ithaca to Rochester, Ny
- Saver
- $20–55
- Flexible
- $40–55
Bus from Ithaca to Buffalo
- Saver
- $29–95
- Flexible
- $55–100
Bus from Ithaca to Buffalo
- Saver
- $28–90
- Flexible
- $55–95
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Ithaca to Toronto
- Ave. Duration
- 7h 45m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Bus from Toronto to Detroit Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Detroit Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 7h 40m
- Frequency
- 4 times a week
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Website
- Greyhound
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $16–24
- Website
- Greyhound
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- +1 607-734-5211
- Website
- CTran
Bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Side
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $3–6
- Website
- CTran
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