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How to get fromJackson to Des Moinesby car, plane, bus, or train

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There are 8 ways to get from Jackson to Des Moines by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Barkley Regional Airport, fly

    best
    1. Drive from Jackson to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Des Moines (DSM)plane plane PAH - DSM
    8h 14m
    $147–699

  2. Drive 580.9 mi

    cheapest
    1. Drive from Jackson to Des Moinescar car 580.9 mi
    10h 46m
    $106–154

  3. Bus

    1. Take the bus from Jackson to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Kansas Citybus bus
    3. Take the bus from Kansas City to Des Moinesbus bus
    17h 35m
    $222–323

  4. Bus to Memphis, fly

    1. Take the bus from Jackson to Memphis - Summer Avebus bus
    2. Fly from Memphis (MEM) to Des Moines (DSM)plane plane MEM - DSM
    9h 15m
    $235–986

  5. Fly from Mc Kellar-Sipes Regional Airport

    1. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Des Moines (DSM)plane plane MKL - DSM
    7h 23m
    $180–771

  6. Bus to Nashville, fly

    1. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - Nashvillebus bus
    2. Fly from Nashville (BNA) to Des Moines (DSM)plane plane BNA - DSM
    7h 34m
    $189–866

  7. Bus, train

    1. Take the bus from Jackson to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Des Moinesbus bus
    19h 36m
    $221–423

  8. Drive, bus

    1. Drive from Jackson Plaza to Shell Gas Station - Blythevillecar car
    2. Take the bus from Shell Gas Station - Blytheville to Marathon Gas Station - Marionbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    4. Take the bus from St Louis Bus Station to Des Moinesbus bus
    20h 34m
    $139–349

Barkley Regional Airport (PAH) to Des Moines (DSM) flights

Calendar28Weekly Planes
Duration7h 36mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Jackson to Des Moines.ExpandLaunch map view
  • Distance: 518.4 mi
  • Duration: 8h 14m

What companies run services between Jackson, TN, USA and Des Moines, IA, USA?

You can take a bus from Jackson Plaza to Des Moines via Lou’s Crawfish, Jackson, Memphis - Summer Ave, Memphis Bus Station, and Kansas City in around 17h 35m. Alternatively, Key Lime, United Airlines, and two other airlines fly from Mc Kellar-Sipes Regional Airport (MKL) to Des Moines (DSM) twice daily.

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