There are 5 ways to get from Jacksonville to Florence by bus (Flixbus), train (Amtrak), car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Jacksonville to Florencebus FlixBus N2472
5h 41m$67–104Bus via Sumter (Greyhound)
cheapest- Take the bus from Jacksonville to Sumter Bus Stopbus Greyhound US0644S
- Take the bus from Sumter Bus Stop to Florence Bus Stationbus Greyhound US0645S
8h 5m$54–102Train (Amtrak)
- Take the train from Jacksonville to Florence Stationtrain Silver Meteor
7h 38m$112–233Drive 307 mi
- Drive from Jacksonville to Florencecar 307 mi
5h 2m$56–81Fly
- Fly from Jacksonville (JAX) to Florence Regional Airport (FLO)plane JAX - FLO
6h 54m$77–396
Jacksonville to Florence by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Jacksonville to Florence is to bus via Sumter which costs $50 - $110 and takes 8h 5m.
The fastest way to get from Jacksonville to Florence is to drive which takes 5h 2m and costs $55 - $85.
No, there is no direct bus from Jacksonville to Florence. However, there are services departing from Jacksonville and arriving at Florence via . The journey, including transfers, takes approximately 5h 41m.
No, there is no direct train from Jacksonville to Florence station. However, there are services departing from Jacksonville and arriving at Florence Station via . The journey, including transfers, takes approximately 7h 38m.
The distance between Jacksonville and Florence is 321 miles. The road distance is 308.7 miles.
The best way to get from Jacksonville to Florence without a car is to bus which takes 5h 41m and costs $65 - $110.
It takes approximately 5h 41m to get from Jacksonville to Florence, including transfers.
Jacksonville to Florence bus services, operated by Flixbus USA, depart from Jacksonville station.
Jacksonville to Florence train services, operated by Amtrak, depart from Jacksonville station.
The best way to get from Jacksonville to Florence is to bus which takes 5h 41m and costs $65 - $110. Alternatively, you can train, which costs $110 - $240 and takes 7h 38m, you could also fly, which costs $75 - $400 and takes 6h 54m.
What companies run services between Jacksonville, FL, USA and Florence, SC, USA?
Flixbus USA operates a bus from Jacksonville to Florence 5 times a week. Tickets cost $50–90 and the journey takes 5h 35m. Alternatively, Amtrak operates a train from Jacksonville to Florence Station once daily. Tickets cost $110–230 and the journey takes 6h 11m.
- Website
- aa.com
Flights from Jacksonville to Florence Regional Airport via Charlotte
- Ave. Duration
- 5h 43m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Florence Station
- Ave. Duration
- 6h 11m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Florence
- Ave. Duration
- 5h 35m
- Frequency
- 5 times a week
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Florence Bus Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
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More Questions & Answers
Jacksonville to Florence bus services, operated by Flixbus USA, arrive at Florence station.
Jacksonville to Florence train services, operated by Amtrak, arrive at Florence Station.
Yes, the driving distance between Jacksonville to Florence is 309 miles. It takes approximately 5h 2m to drive from Jacksonville to Florence.
Book your Jacksonville to Florence train tickets online with Omio.
Book your Jacksonville to Florence bus tickets online with Omio.
There are 49+ hotels available in Florence.