There are 6 ways to get from Jacksonville to Hartsville by bus (Flixbus), train (Amtrak), car, plane, taxi, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Jacksonville to Florencebus FlixBus N2472
6h 3m$112–160Drive 318.4 mi
cheapest- Drive from Jacksonville to Hartsvillecar 318.4 mi
5h 22m$59–84Train (Amtrak)
- Take the train from Jacksonville to Florence Stationtrain Silver Meteor
8h 13m$187–323Fly to Florence Regional Airport, taxi
- Fly from Jacksonville (JAX) to Florence Regional Airport (FLO)plane JAX - FLO
- Take the taxi from Florence Regional Airport (FLO) to Hartsvilletaxi
7h 28m$147–483Bus via Sumter (Greyhound)
- Take the bus from Jacksonville to Sumter Bus Stopbus Greyhound US0644S
- Take the bus from Sumter Bus Stop to Florence Bus Stationbus Greyhound US0645S
8h 39m$129–192Fly to Charlotte Douglas International Airport, bus, taxi
- Fly from Jacksonville (JAX) to Charlotte Douglas International Airport (CLT)plane JAX - CLT
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the taxi from Camden to Hartsvilletaxi
7h 28m$223–732
Jacksonville (JAX) to Florence Regional Airport (FLO) flights
Questions & Answers
The cheapest way to get from Jacksonville to Hartsville is to drive which costs $55 - $85 and takes 5h 22m.
The fastest way to get from Jacksonville to Hartsville is to drive which takes 5h 22m and costs $55 - $85.
No, there is no direct bus from Jacksonville to Hartsville. However, there are services departing from Jacksonville and arriving at Florence via . The journey, including transfers, takes approximately 6h 3m.
No, there is no direct train from Jacksonville to Hartsville station. However, there are services departing from Jacksonville and arriving at Florence Station via . The journey, including transfers, takes approximately 8h 13m.
The distance between Jacksonville and Hartsville is 337 miles. The road distance is 320.3 miles.
The best way to get from Jacksonville to Hartsville without a car is to bus which takes 6h 3m and costs $110 - $160.
It takes approximately 6h 3m to get from Jacksonville to Hartsville, including transfers.
Jacksonville to Hartsville bus services, operated by Flixbus USA, depart from Jacksonville station.
Jacksonville to Hartsville train services, operated by Amtrak, depart from Jacksonville station.
The best way to get from Jacksonville to Hartsville is to bus which takes 6h 3m and costs $110 - $160. Alternatively, you can train, which costs $180 - $330 and takes 8h 13m.
What companies run services between Jacksonville, FL, USA and Hartsville, SC, USA?
Flixbus USA operates a bus from Jacksonville to Florence 5 times a week. Tickets cost $50–90 and the journey takes 5h 35m. Alternatively, Amtrak operates a train from Jacksonville to Florence Station once daily. Tickets cost $110–230 and the journey takes 6h 11m.
- Website
- aa.com
Flights from Jacksonville to Florence Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 43m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–380
Flights from Jacksonville to Charlotte Douglas International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $85–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Florence Station
- Ave. Duration
- 6h 11m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Florence
- Ave. Duration
- 5h 35m
- Frequency
- 5 times a week
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Florence Bus Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
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More Questions & Answers
Jacksonville to Hartsville bus services, operated by Flixbus USA, arrive at Florence station.
Jacksonville to Hartsville train services, operated by Amtrak, arrive at Florence Station.
Yes, the driving distance between Jacksonville to Hartsville is 320 miles. It takes approximately 5h 22m to drive from Jacksonville to Hartsville.
There are seven+ hotels available in Hartsville.