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How to get fromJacksonville to Key Westby plane, bus (Flixbus, Greyhound), train, bus, car, or ferry

Find Transport to Key West

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There are 7 ways to get from Jacksonville to Key West by plane, bus (Flixbus, Greyhound), train, bus, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Jacksonville

    best
    1. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    5h 58m
    $58–286

  2. Bus

    1. Take the bus from Jacksonville to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    16h 11m
    $83–141

  3. Train, bus

    1. Take the train from Jacksonville to Hollywood Amtrak Stationtrain train
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    17h 59m
    $121–278

  4. Drive  503.1 mi

    1. Drive from Jacksonville to Key Westcar car 503.1 mi
    9h 8m
    $92–133

  5. Drive to Orlando Sanford, fly

    1. Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 39m
    $69–316

  6. Bus to Gainesville Regional Airport, fly

    1. Take the bus from Jacksonville to Gainesvillebus bus
    2. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    8h 12m
    $68–320

  7. Bus, ferry

    1. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    17h
    $184–221

Jacksonville to Key West by bus and foot

Calendar19Weekly Services
Duration16h 11mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Jacksonville to Key West.ExpandLaunch map view
  • Distance: 428.5 mi
  • Duration: 5h 58m

What companies run services between Jacksonville, FL, USA and Key West, FL, USA?

Delta and American Airlines fly from Jacksonville (JAX) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Jacksonville to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 16h 11m.

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