There are 8 ways to get from Jacksonville to Key West, FL by plane, bus (Flixbus, Greyhound), train, bus, shuttle, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Jacksonville to Key West International Airport
best- Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane JAX - EYW
6h 55m$437–893Bus
cheapest- Take the bus from Jacksonville to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus Lks
15h 59m$83–160Train, bus, shuttle
- Take the train from Jacksonville to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take a shuttle bus from Big Pine Key, FL to Key West, FL
17h 12m$245–419Drive 504.6 mi
- Drive from Jacksonville to Key West, FLcar 504.6 mi
9h 11m$93–133Drive to Orlando Sanford, fly to Key West International Airport
- Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
4h 51m$133–373Fly Jacksonville to Miami International Airport, shuttle
- Fly from Jacksonville (JAX) to Miami International Airport (MIA)plane JAX - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
8h 16m$227–543Bus to Gainesville Regional Airport, fly to Key West International Airport
- Take the bus from Jacksonville to Gainesvillebus
- Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane GNV - EYW
8h 38m$133–380Bus, ferry
- Take the bus from Jacksonville to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
17h 16m$191–236
Jacksonville to Key West, FL by bus and foot
Questions & Answers
The cheapest way to get from Jacksonville to Key West, FL is to bus which costs $80 - $160 and takes 15h 59m.
The fastest way to get from Jacksonville to Key West, FL is to drive and fly which takes 4h 51m and costs $130 - $380.
No, there is no direct bus from Jacksonville to Key West, FL. However, there are services departing from Jacksonville and arriving at Whitehead & Eaton via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 15h 59m.
The distance between Jacksonville and Key West, FL is 433 miles. The road distance is 507.5 miles.
The best way to get from Jacksonville to Key West, FL without a car is to bus which takes 15h 59m and costs $80 - $160.
It takes approximately 6h 55m to get from Jacksonville to Key West, FL, including transfers.
Jacksonville to Key West, FL bus services, operated by Flixbus USA, depart from Jacksonville station.
The best way to get from Jacksonville to Key West, FL is to fly which takes 6h 55m and costs $430 - $900. Alternatively, you can bus, which costs $80 - $160 and takes 15h 59m.
Jacksonville to Key West, FL bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Jacksonville to Key West, FL is 508 miles. It takes approximately 9h 11m to drive from Jacksonville to Key West, FL.
What companies run services between Jacksonville, FL, USA and Key West, FL, USA?
American Airlines and Delta fly from Jacksonville (JAX) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Jacksonville to Whitehead & Eaton via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 15h 59m.
- Website
- aa.com
Flights from Jacksonville to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $55–320
Flights from Jacksonville to Key West International Airport via Charlotte
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $95–440
Flights from Jacksonville to Miami International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $55–340
Flights from Gainesville Regional Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 29m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–270
Flights from Gainesville Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $85–390
- Website
- delta.com
Flights from Jacksonville to Key West International Airport via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $85–410
Flights from Gainesville Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $75–360
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, and Friday
- Estimated price
- $35–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Hollywood Amtrak Station
- Ave. Duration
- 8h 32m
- Frequency
- Twice daily
- Estimated price
- $130–260
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $60–100
- Schedules at
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 4 times a week
- Estimated price
- $11–18
- Schedules at
- flixbus.com
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $22–40
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to Whitehead & Eaton
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Big Pine Key, FL to Key West, FL
- Ave. Duration
- 30 min
- Frequency
- Once daily
- Estimated price
- $90–110
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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