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How to get fromJacksonville to Key West, FLby plane, bus (Flixbus, Greyhound), train, bus, shuttle, car, or ferry

Find Transport to Key West, FL

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There are 8 ways to get from Jacksonville to Key West, FL by plane, bus (Flixbus, Greyhound), train, bus, shuttle, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Jacksonville to Key West International Airport

    best
    1. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    6h 35m
    $117–343

  2. Drive  504.6 mi

    cheapest
    1. Drive from Jacksonville to Key West, FLcar car 504.6 mi
    9h 11m
    $90–129

  3. Bus

    1. Take the bus from Jacksonville to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus bus Lks
    16h 19m
    $92–152

  4. Train, bus, shuttle

    1. Take the train from Jacksonville to Hollywood Amtrak Stationtrain train
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take a shuttle bus from Big Pine Key, FL to Key West, FLshuttle bus
    17h 12m
    $328–494

  5. Drive to Orlando Sanford, fly to Key West International Airport

    1. Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    4h 48m
    $132–362

  6. Fly Jacksonville to Miami International Airport, shuttle

    1. Fly from Jacksonville (JAX) to Miami International Airport (MIA)plane plane JAX - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    8h 16m
    $212–483

  7. Bus to Gainesville Regional Airport, fly to Key West International Airport

    1. Take the bus from Jacksonville to Gainesvillebus bus
    2. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    8h 57m
    $128–358

  8. Bus, ferry

    1. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    17h 16m
    $191–228

Jacksonville to Key West, FL by bus and foot

Calendar19Weekly Services
Duration16h 19mAverage Duration
Ticket$92Cheapest Price
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Comparing Your Travel Options

Map of how to get from Jacksonville to Key West, FL.ExpandLaunch map view
  • Distance: 430.4 mi
  • Duration: 6h 35m

What companies run services between Jacksonville, FL, USA and Key West, FL, USA?

American Airlines and Delta fly from Jacksonville (JAX) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Jacksonville to Whitehead & Eaton via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 16h 19m.

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