There are 7 ways to get from Jacksonville to Key West (Island) by plane, bus (Flixbus, Greyhound), train, bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Jacksonville
best- Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane JAX - EYW
5h 40m$362–803Drive to Orlando Sanford, fly
cheapest- Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
3h 36m$58–283Bus
- Take the bus from Jacksonville to Miami Airport Stationbus FlixBus 2431
- Take the bus from Miami Airport Station to Key West Airportbus Greyhound US0720s
14h 25m$84–164Train, bus
- Take the train from Jacksonville to Hollywood Amtrak Stationtrain Silver Meteor / ...
- Take the bus from Miami Airport Station to Key West Airportbus Greyhound US0720s
16h 32m$149–319Drive 503.1 mi
- Drive from Jacksonville to Key Westcar 503.1 mi
9h 8m$92–133Bus to Gainesville Regional Airport, fly
- Take the bus from Jacksonville to Gainesvillebus
- Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane GNV - EYW
7h 24m$58–290Bus, ferry
- Take the bus from Jacksonville to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
16h 40m$191–236
Jacksonville to Key West (Island) by bus
Questions & Answers
The cheapest way to get from Jacksonville to Key West (Island) is to bus which costs $80 - $170 and takes 14h 25m.
The fastest way to get from Jacksonville to Key West (Island) is to drive and fly which takes 3h 36m and costs $55 - $290.
No, there is no direct bus from Jacksonville to Key West (Island). However, there are services departing from Jacksonville and arriving at Key West Airport via Miami Airport Station. The journey, including transfers, takes approximately 14h 25m.
The distance between Jacksonville and Key West (Island) is 429 miles. The road distance is 506 miles.
The best way to get from Jacksonville to Key West (Island) without a car is to bus which takes 14h 25m and costs $80 - $170.
It takes approximately 5h 40m to get from Jacksonville to Key West (Island), including transfers.
Jacksonville to Key West (Island) bus services, operated by Flixbus USA, depart from Jacksonville station.
The best way to get from Jacksonville to Key West (Island) is to fly which takes 5h 40m and costs $360 - $850. Alternatively, you can bus, which costs $80 - $170 and takes 14h 25m.
Jacksonville to Key West (Island) bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Jacksonville to Key West (Island) is 506 miles. It takes approximately 9h 8m to drive from Jacksonville to Key West (Island).
What companies run services between Jacksonville, FL, USA and Key West (Island), FL, USA?
American Airlines and Delta fly from Jacksonville (JAX) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Jacksonville to Key West Airport via Miami Airport Station in around 14h 25m.
- Website
- aa.com
Flights from Jacksonville to Key West International Airport via Miami
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $55–320
Flights from Jacksonville to Key West International Airport via Charlotte
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $95–440
Flights from Gainesville Regional Airport to Key West International Airport via Miami
- Ave. Duration
- 3h 29m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–270
Flights from Gainesville Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $85–390
- Website
- delta.com
Flights from Jacksonville to Key West International Airport via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $85–410
Flights from Gainesville Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $75–360
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, and Friday
- Estimated price
- $35–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Hollywood Amtrak Station
- Ave. Duration
- 8h 32m
- Frequency
- Twice daily
- Estimated price
- $120–260
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $60–100
- Schedules at
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 4 times a week
- Estimated price
- $11–18
- Schedules at
- flixbus.com
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–40
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- flixbus.com
- Website
- greyhound.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
- Website
- flixbus.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 9h 15m
- Frequency
- 6 times a week
- Schedules at
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Schedules at
- flixbus.com
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a day
- Schedules at
- flixbus.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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More Questions & Answers
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