What is the cheapest way to get from Jacksonville to Knoxville?

The cheapest way to get from Jacksonville to Knoxville is to drive which costs $90 - $140 and takes 9h 39m.

What is the fastest way to get from Jacksonville to Knoxville?

The fastest way to get from Jacksonville to Knoxville is to fly which takes 3h 31m and costs $160 - $800.

How far is it from Jacksonville to Knoxville?

The distance between Jacksonville and Knoxville is 422 miles. The road distance is 510.6 miles.

How long does it take to get from Jacksonville to Knoxville?

It takes approximately 3h 31m to get from Jacksonville to Knoxville, including transfers.

Can I drive from Jacksonville to Knoxville?

Yes, the driving distance between Jacksonville to Knoxville is 511 miles. It takes approximately 9h 39m to drive from Jacksonville to Knoxville.

Where can I stay near Knoxville?

There are 319+ hotels available in Knoxville.

Jacksonville to Knoxville - 7 ways to travel via plane, bus, shuttle, and car

How to get fromJacksonville to Knoxville

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There are 7 ways to get from Jacksonville to Knoxville by plane, bus, shuttle, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly Jacksonville to Mcghee Tyson Airport
best
1. Fly from Jacksonville (JAX) to Mcghee Tyson Airport (TYS)plane JAX - TYS
3h 31m
$167–773
Drive 507.6 mi
cheapest
1. Drive from Jacksonville to Knoxvillecar 507.6 mi
9h 39m
$93–134
Bus, shuttle, drive
1. Take the bus from Jacksonville to Charlotte Bus Stationbus
2. Take the bus from Charlotte to Boonebus
3. Take a shuttle bus from Boone to Black Bear Resortshuttle
4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle
5. Drive from Hot Springs to Knoxvillecar
16h 34m
Drive to Orlando Sanford, fly to Mcghee Tyson Airport
1. Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar
2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
4h 14m
$188–753
Fly Jacksonville to Nashville, drive
1. Fly from Jacksonville (JAX) to Nashville (BNA)plane JAX - BNA
2. Drive from Nashville-Airport-BNA to Knoxvillecar
6h 20m
$107–483
Bus to Gainesville Regional Airport, fly to Mcghee Tyson Airport
1. Take the bus from Jacksonville to Gainesvillebus
2. Fly from Gainesville Regional Airport (GNV) to Mcghee Tyson Airport (TYS)plane GNV - TYS
7h 36m
$168–690
Bus, taxi, shuttle, drive
1. Take the bus from Jacksonville to Camdenbus
2. Take the bus from Camden to Charlotte Bus Stationbus
3. Take the bus from Charlotte to Boonebus
4. Take the taxi from Boone to Black Bear Resorttaxi
5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle
6. Drive from Hot Springs to Chilhowee at Holstoncar
19h 23m

Jacksonville (JAX) to Mcghee Tyson Airport (TYS) flights

6Weekly Planes

2h 22mAverage Duration

$114Cheapest Price

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Questions & Answers

Map of how to get from Jacksonville to Knoxville.

Launch map view

Distance: 419.7 mi
Duration: 3h 31m

What companies run services between Jacksonville, FL, USA and Knoxville, TN, USA?

Allegiant Air, Delta, and Southwest Airlines fly from Jacksonville (JAX) to Mcghee Tyson Airport (TYS) 6 times a week.

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