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How to get fromJacksonville to Lake Cityby bus, taxi, train (Amtrak), car, or plane

Find Transport to Lake City

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There are 5 ways to get from Jacksonville to Lake City by bus, taxi, train (Amtrak), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Jacksonville to Florencebus bus FlixBus N2472
    2. Take the taxi from Florence to Lake Citytaxi taxi
    6h 13m
    $129–180

  2. Drive 298.2 mi

    cheapest
    1. Drive from Jacksonville to Lake Citycar car 298.2 mi
    4h 57m
    $55–79

  3. Train (Amtrak)

    1. Take the train from Jacksonville to Kingstree Stationtrain train Silver Meteor
    7h
    $142–263

  4. Fly to Florence Regional Airport, taxi

    1. Fly from Jacksonville (JAX) to Florence Regional Airport (FLO)plane plane JAX - FLO
    2. Take the taxi from Florence Regional Airport (FLO) to Lake Citytaxi taxi
    7h 28m
    $142–473

  5. Fly to Myrtle Beach, drive

    1. Fly from Jacksonville (JAX) to Myrtle Beach (MYR)plane plane JAX - MYR
    2. Drive from Myrtle Beach (MYR) to Lake Citycar car
    6h 40m
    $283–869

Jacksonville (JAX) to Florence Regional Airport (FLO) flights

Calendar7Weekly Planes
Duration5h 43mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Jacksonville to Lake City.ExpandLaunch map view
  • Distance: 342.2 mi
  • Duration: 6h 13m

What companies run services between Jacksonville, FL, USA and Lake City, SC, USA?

Amtrak operates a train from Jacksonville to Kingstree Station once daily. Tickets cost $95–200 and the journey takes 5h 14m.

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