There are 5 ways to get from Jacksonville to Orangeburg by bus (Flixbus, Greyhound), train (Amtrak), car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Jacksonville to Orangeburgbus FlixBus 2433
4h 28m$47–84Drive 238.8 mi
cheapest- Drive from Jacksonville to Orangeburgcar 238.8 mi
4h 23m$44–63Train (Amtrak)
- Take the train from Jacksonville to Denmark Amtrak Stationtrain Floridian
6h 24m$142–243Fly to Columbia, taxi
- Fly from Jacksonville (JAX) to Columbia (CAE)plane JAX - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
5h 55m$272–1,053Fly to Augusta Regional Airport At Bush Field, drive
- Fly from Jacksonville (JAX) to Augusta Regional Airport At Bush Field (AGS)plane JAX - AGS
- Drive from Augusta Regional Airport At Bush Field (AGS) to Orangeburgcar
7h$76–394
Jacksonville (JAX) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Jacksonville to Orangeburg is to drive which costs $40 - $65 and takes 4h 23m.
The fastest way to get from Jacksonville to Orangeburg is to drive which takes 4h 23m and costs $40 - $65.
No, there is no direct bus from Jacksonville to Orangeburg. However, there are services departing from Jacksonville and arriving at Orangeburg via . The journey, including transfers, takes approximately 4h 28m.
No, there is no direct train from Jacksonville to Orangeburg station. However, there are services departing from Jacksonville and arriving at Denmark Amtrak Station via . The journey, including transfers, takes approximately 6h 24m.
The distance between Jacksonville and Orangeburg is 249 miles. The road distance is 240.1 miles.
The best way to get from Jacksonville to Orangeburg without a car is to bus which takes 4h 28m and costs $45 - $85.
It takes approximately 4h 28m to get from Jacksonville to Orangeburg, including transfers.
Jacksonville to Orangeburg bus services, operated by Flixbus USA, depart from Jacksonville station.
Jacksonville to Orangeburg train services, operated by Amtrak, depart from Jacksonville station.
The best way to get from Jacksonville to Orangeburg is to bus which takes 4h 28m and costs $45 - $85. Alternatively, you can train, which costs $140 - $250 and takes 6h 24m.
What companies run services between Jacksonville, FL, USA and Orangeburg, SC, USA?
Flixbus USA operates a bus from Jacksonville to Orangeburg once daily. Tickets cost $40–65 and the journey takes 4h 25m. Greyhound USA also services this route once daily. Alternatively, Amtrak operates a train from Jacksonville to Denmark Amtrak Station once daily. Tickets cost $75–160 and the journey takes 4h 29m.
- Website
- delta.com
Flights from Jacksonville to Columbia via Atlanta
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $160–950
Flights from Jacksonville to Columbia via New York La Guardia
- Ave. Duration
- 7h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $360–1,600
Flights from Jacksonville to Augusta Regional Airport At Bush Field via Atlanta
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $60–370
- Website
- aa.com
Flights from Jacksonville to Columbia via Charlotte
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $150–900
Flights from Jacksonville to Columbia via Miami
- Ave. Duration
- 5h 30m
- When
- Saturday
- Estimated price
- $250–1,200
Flights from Jacksonville to Columbia via New York La Guardia
- Ave. Duration
- 7h 26m
- When
- Saturday and Sunday
- Estimated price
- $360–1,600
Flights from Jacksonville to Augusta Regional Airport At Bush Field via Charlotte
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $65–390
Flights from Jacksonville to Augusta Regional Airport At Bush Field via Dallas/Ft.Worth
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $170–700
- Website
- united.com
Flights from Jacksonville to Columbia via Washington Dulles
- Ave. Duration
- 6h 6m
- When
- Friday and Saturday
- Estimated price
- $270–1,300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Denmark Amtrak Station
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Orangeburg
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $40–65
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Orangeburg
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Want to know more about travelling around United States
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More Questions & Answers
Jacksonville to Orangeburg bus services, operated by Flixbus USA, arrive at Orangeburg station.
Jacksonville to Orangeburg train services, operated by Amtrak, arrive at Denmark Amtrak Station.
Yes, the driving distance between Jacksonville to Orangeburg is 240 miles. It takes approximately 4h 23m to drive from Jacksonville to Orangeburg.
Book your Jacksonville to Orangeburg bus tickets online with Omio.
There are 22+ hotels available in Orangeburg.






