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How to get fromJacksonville to Santa Anaby plane, bus (Greyhound, Flixbus), bus, train, car, bus (Flixbus, Greyhound, Amtrak), or train (Amtrak)

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There are 9 ways to get from Jacksonville to Santa Ana by plane, bus (Greyhound, Flixbus), bus, train, car, bus (Flixbus, Greyhound, Amtrak), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Jacksonville (JAX) to John Wayne Airport Orange County (SNA)plane plane JAX - SNA
    9h 15m
    $201–788

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Jacksonville (JAX) to Los Angeles International Airport (LAX)plane plane JAX - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    10h 15m
    $128–476

  3. Bus via Ciudad Juárez

    1. Take the bus from Jacksonville to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to Downtown Houstonbus bus
    3. Take the bus from Houston, TX - Houston Airline Dr to El Paso, TX - Tornado Bus Cobus bus
    4. Take the bus from El Paso to Santa Anabus bus
    2d 5h
    $430–588

  4. Bus, train

    1. Take the bus from Jacksonville to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Los Angelestrain train
    4. Take the train from Los Angeles to Santa Anatrain train
    2d 16h
    $1,220–1,886

  5. Drive  2,360.9 mi

    1. Drive from Jacksonville to Santa Anacar car 2,360.9 mi
    38h 9m
    $418–603

  6. Fly to San Diego International Airport, train

    1. Fly from Jacksonville (JAX) to San Diego International Airport (SAN)plane plane JAX - SAN
    2. Take the train from San Diego to Santa Anatrain train
    10h 42m
    $184–688

  7. Fly to Long Beach Airport

    1. Fly from Jacksonville (JAX) to Long Beach Airport (LGB)plane plane JAX - LGB
    12h 10m
    $157–660

  8. Bus

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to Santa Anabus bus
    2d 10h

  9. Train (Amtrak)

    1. Take the train from Jacksonville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3d 9h
    $2,058–3,312

Jacksonville to Santa Ana by bus and train

Calendar3Weekly Services
Duration2d 16hAverage Duration
Ticket$1,220Cheapest Price
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Comparing Your Travel Options

Map of how to get from Jacksonville to Santa Ana.ExpandLaunch map view
  • Distance: 2,140.6 mi
  • Duration: 9h 15m

What companies run services between Jacksonville, FL, USA and Santa Ana, CA, USA?

United Airlines, Southwest Airlines, and three other airlines fly from Jacksonville (JAX) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Jacksonville to Santa Ana via Mobile Bus Station, Downtown Houston, St Joseph Pkwy @ Louisiana St, N Main St @ Airline Dr, Houston, TX - Houston Airline Dr, El Paso, TX - Tornado Bus Co, and El Paso in around 2d 5h.

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Bus operators

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