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How to get fromJacksonville to Sikestonby plane, bus, taxi, or car

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There are 8 ways to get from Jacksonville to Sikeston by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Jacksonville to Lambert–St. Louis International Airport, bus, taxi

    best
    1. Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane plane JAX - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    8h 33m
    $216–711

  2. Fly Jacksonville to Nashville, bus, drive

    cheapest
    1. Fly from Jacksonville (JAX) to Nashville (BNA)plane plane JAX - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    8h 56m
    $100–446

  3. Bus, drive

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    15h 58m
    $131–210

  4. Drive  749.5 mi

    1. Drive from Jacksonville to Sikestoncar car 749.5 mi
    13h 40m
    $129–185

  5. Drive to Orlando Sanford, fly to Cape Girardeau Municipal Airport, taxi

    1. Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Cape Girardeau Municipal Airport (CGI)plane plane SFB - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    5h 12m
    $351–931

  6. Fly Jacksonville to Cape Girardeau Municipal Airport, taxi

    1. Fly from Jacksonville (JAX) to Cape Girardeau Municipal Airport (CGI)plane plane JAX - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    8h 45m
    $177–563

  7. Fly Jacksonville to Midamerica St. Louis Airport, bus, taxi

    1. Fly from Jacksonville (JAX) to Midamerica St. Louis Airport (BLV)plane plane JAX - BLV
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    8h 48m
    $209–570

  8. Bus, taxi

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    20h 25m
    $246–384

Jacksonville (JAX) to Lambert–St. Louis International Airport (STL) flights

Calendar72Weekly Planes
Duration4h 22mAverage Duration
Ticket$100Cheapest Price
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Map of how to get from Jacksonville to Sikeston.ExpandLaunch map view
  • Distance: 930 mi
  • Duration: 8h 33m

What companies run services between Jacksonville, FL, USA and Sikeston, MO, USA?

There is no direct connection from Jacksonville to Sikeston. However, you can take the line 1 bus to Jia, walk to Jacksonville (JAX) airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to CIVIC CENTER station, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston. Alternatively, you can take a bus from Jacksonville to Sikeston via Atlanta Bus Station and Paducah Bus Station in around 15h 58m.

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