There are 7 ways to get from Jacksonville to Sikeston by plane, bus, taxi, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Jacksonville to Lambert–St. Louis International Airport, bus, taxi
best- Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane JAX - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
8h 28m$210–706Fly Jacksonville to Nashville, bus, drive
cheapest- Fly from Jacksonville (JAX) to Nashville (BNA)plane JAX - BNA
- Take the bus from Nashville Bus Station to Paducah Bus Stationbus
- Drive from Paducah Bus Station to Sikestoncar
8h 56m$100–447Bus, drive
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Paducah Bus Stationbus
- Drive from Paducah Bus Station to Sikestoncar
15h 53m$125–206Drive 749.5 mi
- Drive from Jacksonville to Sikestoncar 749.5 mi
13h 40m$137–198Drive to Orlando Sanford, fly to Cape Girardeau Municipal Airport, taxi
- Drive from Jacksonville to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Cape Girardeau Municipal Airport (CGI)plane SFB - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi
5h 12m$293–983Fly Jacksonville to Memphis, bus
- Fly from Jacksonville (JAX) to Memphis (MEM)plane JAX - MEM
- Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus
10h 34m$198–819Fly Jacksonville to Midamerica St. Louis Airport, bus, taxi
- Fly from Jacksonville (JAX) to Midamerica St. Louis Airport (BLV)plane JAX - BLV
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
8h 48m$208–565
Jacksonville (JAX) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Jacksonville to Sikeston is to bus and drive which costs $120 - $210 and takes 15h 53m.
The fastest way to get from Jacksonville to Sikeston is to drive and fly and taxi which takes 5h 12m and costs $290 - $1,000.
The distance between Jacksonville and Sikeston is 935 miles. The road distance is 753.8 miles.
It takes approximately 8h 28m to get from Jacksonville to Sikeston, including transfers.
Sikeston is 1h behind Jacksonville. It is currently 8:03 AM in Jacksonville and 7:03 AM in Sikeston.
Yes, the driving distance between Jacksonville to Sikeston is 754 miles. It takes approximately 13h 40m to drive from Jacksonville to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Jacksonville, FL, USA and Sikeston, MO, USA?
There is no direct connection from Jacksonville to Sikeston. However, you can take the line 1 bus to Jia, walk to Jacksonville (JAX) airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to CIVIC CENTER station, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston. Alternatively, you can take a bus from Jacksonville to Sikeston via Atlanta Bus Station and Paducah Bus Station in around 15h 53m.
- Website
- southwest.com
Flights from Jacksonville to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $95–550
Flights from Jacksonville to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 58m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Jacksonville to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- $120–600
Flights from Jacksonville to Nashville
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $65–390
Flights from Jacksonville to Memphis via Nashville
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $130–750
Flights from Jacksonville to Memphis via Dallas
- Ave. Duration
- 5h 30m
- When
- Sunday
- Estimated price
- $200–950
Flights from Jacksonville to Memphis via Houston Hobby Apt
- Ave. Duration
- 7h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–950
- Website
- delta.com
Flights from Jacksonville to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $95–550
Flights from Jacksonville to Nashville via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $65–390
Flights from Jacksonville to Memphis via Atlanta
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $120–700
- Website
- aa.com
Flights from Jacksonville to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $100–550
Flights from Jacksonville to Nashville via Charlotte
- Ave. Duration
- 3h 47m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–420
Flights from Jacksonville to Memphis via Charlotte
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $140–800
- Website
- contouraviation.com
Flights from Orlando Sanford to Cape Girardeau Municipal Airport
- Ave. Duration
- 2h 20m
- When
- Wednesday and Saturday
- Estimated price
- $190–850
- Website
- allegiantair.com
Flights from Jacksonville to Midamerica St. Louis Airport
- Ave. Duration
- 2h 6m
- When
- Thursday and Sunday
- Estimated price
- $70–380
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Paducah Bus Station
- Ave. Duration
- 6h 51m
- Frequency
- 5 times a week
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Nashville Bus Station to Paducah Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Tornado Bus Co - West Memphis to Flying J - Matthews
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $26–50
- Schedules at
- Tornado Bus Company
- Adult
- $26–50
- Ave. Duration
- 34 min
- Estimated price
- $80–120
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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