There are 5 ways to get from Jacksonville to Sikeston by plane, bus, taxi, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Lambert–St. Louis International Airport, bus, taxi
best- Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane JAX - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
8h 23m$212–706Fly to Nashville, bus, drive
cheapest- Fly from Jacksonville (JAX) to Nashville (BNA)plane JAX - BNA
- Take the bus from Nashville Bus Station to Paducah Bus Stationbus
- Drive from Paducah Bus Station to Sikestoncar
8h 51m$100–447Bus, drive
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Paducah Bus Stationbus
- Drive from Paducah Bus Station to Sikestoncar
15h 53m$123–208Drive 749.5 mi
- Drive from Jacksonville to Sikestoncar 749.5 mi
13h 40m$137–198Fly to Memphis, bus
- Fly from Jacksonville (JAX) to Memphis (MEM)plane JAX - MEM
- Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus
10h 34m$198–819
Jacksonville (JAX) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Jacksonville to Sikeston is to bus and drive which costs $120 - $210 and takes 15h 53m.
The fastest way to get from Jacksonville to Sikeston is to fly and bus and taxi which takes 8h 23m and costs $210 - $750.
The distance between Jacksonville and Sikeston is 935 miles. The road distance is 753.8 miles.
It takes approximately 8h 23m to get from Jacksonville to Sikeston, including transfers.
Sikeston is 1h behind Jacksonville. It is currently 10:04 AM in Jacksonville and 9:04 AM in Sikeston.
Yes, the driving distance between Jacksonville to Sikeston is 754 miles. It takes approximately 13h 40m to drive from Jacksonville to Sikeston.
There are 12+ hotels available in Sikeston.
What companies run services between Jacksonville, FL, USA and Sikeston, MO, USA?
There is no direct connection from Jacksonville to Sikeston. However, you can take the line 1 bus to Jia, walk to Jacksonville (JAX) airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to CIVIC CENTER station, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston. Alternatively, you can take a bus from Jacksonville to Sikeston via Atlanta Bus Station and Paducah Bus Station in around 15h 53m.
- Website
- southwest.com
Flights from Jacksonville to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from Jacksonville to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $100–550
Flights from Jacksonville to Nashville
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $65–390
Flights from Jacksonville to Memphis via Nashville
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $130–750
Flights from Jacksonville to Memphis via Dallas
- Ave. Duration
- 6h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $210–950
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–30
- Website
- Greyhound
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- $60–110
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide


