There are 5 ways to get from Jefferson City to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Columbia Regional Airport to Chicago O'Hare International Airport
best- Fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD)plane COU - ORD
2h 45m$124–352Drive 386.2 mi
cheapest- Drive from Jefferson City to Chicagocar 386.2 mi
7h 1m$71–102Train (Amtrak)
- Take the train from Jefferson City Station to Chicago Union Stationtrain Lincoln Service Missouri River Runner
8h 11m$130–270Bus
- Take the bus from Jefferson City to St Louis Bus Stationbus Greyhound US0175s
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus 2510 / ...
10h 48m$86–150Shuttle to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport
- Take a shuttle bus from Jefferson City, Missouri to St Louis International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
4h 46m$194–511
Jefferson City to Chicago by train (Amtrak)
Questions & Answers
The cheapest way to get from Jefferson City to Chicago is to drive which costs $70 - $110 and takes 7h 1m.
The fastest way to get from Jefferson City to Chicago is to fly which takes 2h 45m and costs $120 - $360.
No, there is no direct bus from Jefferson City to Chicago station. However, there are services departing from Jefferson City and arriving at Chicago Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 10h 48m.
Yes, there is a direct train departing from Jefferson City Station station and arriving at Chicago Union Station station. Services depart once daily, and operate every day. The journey takes approximately 8h 11m.
The distance between Jefferson City and Chicago is 355 miles. The road distance is 388.4 miles.
The best way to get from Jefferson City to Chicago without a car is to train which takes 8h 11m and costs $130 - $270.
It takes approximately 2h 45m to get from Jefferson City to Chicago, including transfers.
Jefferson City to Chicago bus services, operated by Greyhound USA, depart from Jefferson City station.
Jefferson City to Chicago train services, operated by Amtrak, depart from Jefferson City Station.
The best way to get from Jefferson City to Chicago is to fly which takes 2h 45m and costs $120 - $360. Alternatively, you can train, which costs $130 - $270 and takes 8h 11m, you could also bus, which costs $85 - $150 and takes 10h 48m.
What companies run services between Jefferson City, MO, USA and Chicago, IL, USA?
American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, Amtrak operates a train from Jefferson City Station to Chicago Union Station once daily. Tickets cost $130–270 and the journey takes 8h 11m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $55–360
- Website
- aa.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $40–250
- Website
- united.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $40–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jefferson City Station to Chicago Union Station
- Ave. Duration
- 8h 11m
- Frequency
- Once daily
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jefferson City to St Louis Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- flixbus.com
- Phone
- 573-368-4656
- [email protected]
- Website
- usaxonline.com
Shuttle from Jefferson City, Missouri to St Louis International Airport
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $135–150
- Website
- https://usaxonline.com/
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More Questions & Answers
Jefferson City to Chicago bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Jefferson City to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Jefferson City to Chicago is 388 miles. It takes approximately 7h 1m to drive from Jefferson City to Chicago.
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