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How to get fromJefferson City to Des Moinesby bus (Greyhound), train, bus, car, plane, or shuttle

Find Transport to Des Moines

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There are 6 ways to get from Jefferson City to Des Moines by bus (Greyhound), train, bus, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Jefferson City to Kansas City Bus Stationbus bus Greyhound US0175s
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 802 / ...
    7h 8m
    $82–130

  2. Drive 254.9 mi

    cheapest
    1. Drive from Jefferson City to Des Moinescar car 254.9 mi
    5h 11m
    $47–68

  3. Train, bus

    1. Take the train from Jefferson City Station to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 802 / ...
    8h 1m
    $101–178

  4. Fly from Columbia Regional Airport

    1. Fly from Columbia Regional Airport (COU) to Des Moines (DSM)plane plane COU - DSM
    4h 46m
    $209–718

  5. Train, bus via Des Moines

    1. Take the train from Jefferson City Station to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson 802 / ...
    8h 1m
    $81–163

  6. Shuttle to Lambert–St. Louis International Airport, fly

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    6h 31m
    $294–917

Jefferson City to Des Moines by train, foot, and bus

Calendar14Weekly Services
Duration8h 1mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Des Moines.ExpandLaunch map view
  • Distance: 344.6 mi
  • Duration: 7h 8m

What companies run services between Jefferson City, MO, USA and Des Moines, IA, USA?

You can take a vehicle from Jefferson City to Des Moines via Jefferson City, Kansas City Bus Station, and Kansas City in around 7h 8m. Alternatively, United Airlines and American Airlines fly from Columbia Regional Airport (COU) to Des Moines (DSM) every 3 hours.

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Need to know: Greyhound

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