There are 4 ways to get from Jefferson City to Effingham by train, bus, bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Jefferson City Station to St. Louistrain Missouri River Runner / ...
- Take the bus from St Louis Bus Station to Effinghambus Greyhound US0421
5h 18m$55–109Drive 222 mi
cheapest- Drive from Jefferson City to Effinghamcar 222 mi
3h 56m$41–59Bus
- Take the bus from Jefferson City to St Louis Bus Stationbus Greyhound US0175s
- Take the bus from St Louis Bus Station to Effinghambus Greyhound US0421
6h 28m$51–95Fly, train
- Fly from Columbia Regional Airport (COU) to University Of Illinois Willard Airport (CMI)plane COU - CMI
- Take the train from Champaign-Urbana to Effingham Stationtrain
6h 21m$178–500
Jefferson City to Effingham by train and bus
Questions & Answers
The cheapest way to get from Jefferson City to Effingham is to drive which costs $40 - $60 and takes 3h 56m.
The fastest way to get from Jefferson City to Effingham is to drive which takes 3h 56m and costs $40 - $60.
No, there is no direct bus from Jefferson City to Effingham. However, there are services departing from Jefferson City and arriving at Effingham via St Louis Bus Station. The journey, including transfers, takes approximately 6h 28m.
The distance between Jefferson City and Effingham is 223 miles. The road distance is 223.3 miles.
The best way to get from Jefferson City to Effingham without a car is to train and bus which takes 5h 18m and costs $50 - $110.
It takes approximately 5h 18m to get from Jefferson City to Effingham, including transfers.
Jefferson City to Effingham bus services, operated by Greyhound-us, depart from Jefferson City station.
Jefferson City to Effingham bus services, operated by Greyhound-us, arrive at St Louis Bus Station.
Yes, the driving distance between Jefferson City to Effingham is 223 miles. It takes approximately 3h 56m to drive from Jefferson City to Effingham.
Book your Jefferson City to Effingham bus tickets online with Omio.
What companies run services between Jefferson City, MO, USA and Effingham, IL, USA?
You can take a vehicle from Jefferson City to Effingham via Jefferson City and St Louis Bus Station in around 6h 28m.
- Website
- aa.com
Flights from Columbia Regional Airport to University Of Illinois Willard Airport via Chicago O'Hare
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $55–330
Flights from Columbia Regional Airport to University Of Illinois Willard Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $100–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jefferson City Station to St. Louis
- Ave. Duration
- 2h 33m
- Frequency
- Twice daily
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
Train from Champaign-Urbana to Effingham Station
- Ave. Duration
- 1h 7m
- Frequency
- 3 times a day
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Effingham
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
Bus from Jefferson City to St Louis Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Effingham
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Jefferson City to St Louis Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Schedules at
- greyhound.com
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More Questions & Answers
There are 18+ hotels available in Effingham.






