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How to get fromJefferson City to Great Smoky Mountainsby plane, car, train, bus, or shuttle

Find Transport to Great Smoky Mountains

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There are 7 ways to get from Jefferson City to Great Smoky Mountains by plane, car, train, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Columbia Regional Airport to Mcghee Tyson Airport, drive

    best
    1. Fly from Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS)plane plane COU - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 53m
    $242–913

  2. Drive 635.2 mi

    cheapest
    1. Drive from Jefferson City to Great Smoky Mountainscar car 635.2 mi
    12h 40m
    $116–168

  3. Train, bus, drive

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    28h 6m
    $197–400

  4. Train, bus, drive via Chicago

    1. Take the train from Jefferson City Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    42h 16m
    $515–1,133

  5. Fly Columbia Regional Airport to Asheville Regional Airport, drive

    1. Fly from Columbia Regional Airport (COU) to Asheville Regional Airport (AVL)plane plane COU - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 51m
    $171–529

  6. Shuttle to Lambert–St. Louis International Airport, fly to Mcghee Tyson Airport, drive

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    8h 50m
    $277–1,012

  7. Train, bus, drive via Carbondale

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    28h 50m
    $202–405

Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS) flights

Calendar62Weekly Planes
Duration5h 18mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 577.2 mi
  • Duration: 6h 53m

What companies run services between Jefferson City, MO, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Jefferson City to Great Smoky Mountains. However, you can take the taxi to Columbia Regional Airport (COU) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a train from Jefferson City Station to Great Smoky Mountains via St. Louis, St Louis Bus Station, Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 28h 6m.

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