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How to get fromJefferson City to Key Westby plane, train, bus, car, shuttle, or ferry

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There are 6 ways to get from Jefferson City to Key West by plane, train, bus, car, shuttle, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Columbia Regional Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Key West International Airport (EYW)plane plane COU - EYW
    8h 23m
    $193–550

  2. Train, bus via Atlanta

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    36h 39m
    $262–514

  3. Train, bus

    1. Take the train from Jefferson City Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 14h
    $822–1,731

  4. Drive 1,447.5 mi

    1. Drive from Jefferson City to Key Westcar car 1,447.5 mi
    26h 36m
    $265–382

  5. Shuttle to Lambert–St. Louis International Airport, fly

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane plane STL - EYW
    7h 31m
    $258–709

  6. Train, bus, ferry

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Fort Myersbus bus
    5. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    42h 5m
    $471–685

Jefferson City to Key West by train, bus, and foot

Calendar12Weekly Services
Duration36h 39mAverage Duration
Ticket$262Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Key West.ExpandLaunch map view
  • Distance: 1,182.3 mi
  • Duration: 8h 23m

What companies run services between Jefferson City, MO, USA and Key West, FL, USA?

United Airlines and American Airlines fly from Columbia Regional Airport (COU) to Key West International Airport (EYW) every 4 hours.

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