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How to get fromJefferson City to Mobileby plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Jefferson City to Mobile by plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Columbia Regional Airport to Mobile Regional Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Mobile Regional Airport (MOB)plane plane COU - MOB
    8h 37m
    $177–547

  2. Drive 694.3 mi

    cheapest
    1. Drive from Jefferson City to Mobilecar car 694.3 mi
    13h 28m
    $127–183

  3. Train, bus

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    24h 6m
    $180–390

  4. Train, bus via Carbondale

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    24h 9m
    $285–630

  5. Shuttle to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    6h 52m
    $246–654

  6. Fly Columbia Regional Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Columbia Regional Airport (COU) to Destin–Fort Walton Beach Airport (VPS)plane plane COU - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    4h 26m
    $171–505

  7. Shuttle to Lambert–St. Louis International Airport, fly to Pensacola International Airport, bus

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    3. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 32m
    $226–595

  8. Shuttle to Lambert–St. Louis International Airport, fly to Northwest Florida Beaches International Airport, drive

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    3. Drive from Northwest Florida Beaches International Airport (ECP) to Mobilecar car
    8h 2m
    $255–671

  9. Train to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    8h 34m
    $150–499

  10. Bus

    1. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    26h 27m
    $168–330

Jefferson City to Mobile by train and bus

Calendar7Weekly Services
Duration24h 6mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Mobile.ExpandLaunch map view
  • Distance: 649.3 mi
  • Duration: 8h 37m

What companies run services between Jefferson City, MO, USA and Mobile, AL, USA?

American Airlines flies from Columbia Regional Airport (COU) to Mobile Regional Airport (MOB) 3 times a day. Alternatively, you can take a vehicle from Jefferson City to Water NB at St Louis St via Jefferson City, St Louis Bus Station, New Orleans Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 26h 27m.

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