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How to get fromJefferson City to Muscatineby plane, taxi, train, bus, or car

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There are 6 ways to get from Jefferson City to Muscatine by plane, taxi, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Quad City International Airport, taxi

    best
    1. Fly from Columbia Regional Airport (COU) to Quad City International Airport (MLI)plane plane COU - MLI
    2. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    4h 55m
    $237–567

  2. Drive  245.8 mi

    cheapest
    1. Drive from Jefferson City to Muscatinecar car 245.8 mi
    4h 47m
    $45–65

  3. Train, bus, drive (Amtrak)

    1. Take the train from Jefferson City Station to Springfieldtrain train
    2. Take the bus from Springfield to Galesburg Amtrak Stationbus bus
    3. Drive from Galesburg Amtrak Station to Muscatinecar car
    9h 53m
    $97–186

  4. Bus, taxi

    1. Take the bus from Jefferson City to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Iowa Citybus bus
    4. Take the taxi from Iowa City to Muscatinetaxi taxi
    11h 15m
    $209–287

  5. Fly to The Eastern Iowa Airport, drive

    1. Fly from Columbia Regional Airport (COU) to The Eastern Iowa Airport (CID)plane plane COU - CID
    2. Drive from Cedar-Rapids-Airport-CID to Muscatinecar car
    5h 25m
    $152–473

  6. Train, drive (Amtrak)

    1. Take the train from Jefferson City Station to Kansas Citytrain train
    2. Take the train from Kansas City to Galesburg Amtrak Stationtrain train
    3. Drive from Galesburg Amtrak Station to Muscatinecar car
    10h 24m
    $122–267

Columbia Regional Airport (COU) to Quad City International Airport (MLI) flights

Calendar49Weekly Planes
Duration5h 25mAverage Duration
Ticket$58Cheapest Price
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Comparing Your Travel Options

Map of how to get from Jefferson City to Muscatine.ExpandLaunch map view
  • Distance: 256.6 mi
  • Duration: 4h 55m

What companies run services between Jefferson City, MO, USA and Muscatine, IA, USA?

There is no direct connection from Jefferson City to Muscatine. However, you can take the taxi to Columbia Regional Airport (COU) airport, fly to Quad City International Airport (MLI), then take the taxi to Muscatine. Alternatively, you can take a train from Jefferson City Station to Muscatine via Springfield, Springfield, and Galesburg Amtrak Station in around 9h 53m.

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