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How to get fromJefferson City to Myrtle Beachby plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Jefferson City to Myrtle Beach by plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Columbia Regional Airport to Myrtle Beach

    best
    1. Fly from Columbia Regional Airport (COU) to Myrtle Beach (MYR)plane plane COU - MYR
    5h 39m
    $163–491

  2. Train, bus via Atlanta

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    24h 18m
    $217–336

  3. Train, bus

    1. Take the train from Jefferson City Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    39h 24m
    $817–1,355

  4. Drive  978.5 mi

    1. Drive from Jefferson City to Myrtle Beachcar car 978.5 mi
    18h 24m
    $173–250

  5. Shuttle to Lambert–St. Louis International Airport, fly to Myrtle Beach

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    4h 56m
    $228–590

  6. Fly Columbia Regional Airport to Florence Regional Airport, bus

    1. Fly from Columbia Regional Airport (COU) to Florence Regional Airport (FLO)plane plane COU - FLO
    2. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    9h 6m
    $181–541

  7. Bus

    1. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    26h 3m
    $194–320

Jefferson City to Myrtle Beach by train and bus

Calendar10Weekly Services
Duration24h 18mAverage Duration
Ticket$217Cheapest Price
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Comparing Your Travel Options

Map of how to get from Jefferson City to Myrtle Beach.ExpandLaunch map view
  • Distance: 843.6 mi
  • Duration: 5h 39m

What companies run services between Jefferson City, MO, USA and Myrtle Beach, SC, USA?

American Airlines flies from Columbia Regional Airport (COU) to Myrtle Beach (MYR) 3 times a day. Alternatively, you can take a vehicle from Jefferson City to Myrtle Beach Bus Station via Jefferson City, St Louis Bus Station, and Atlanta Bus Station in around 26h 3m.

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