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How to get fromJefferson City to Sanibel Islandby plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Jefferson City to Sanibel Island by plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Columbia Regional Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Ft. Myers (RSW)plane plane COU - RSW
    6h 31m
    $277–737

  2. Drive 1,221.3 mi

    cheapest
    1. Drive from Jefferson City to Sanibel Islandcar car 1,221.3 mi
    22h 21m
    $223–322

  3. Train, bus

    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to University of South Floridabus bus
    4. Take the bus from University of South Florida - 3801 USF Holly Dr to Fort Myers 7-11bus bus
    28h 18m
    $294–515

  4. Shuttle to Lambert–St. Louis International Airport, fly

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    6h 5m
    $342–886

  5. Bus

    1. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    31h 47m
    $256–443

Columbia Regional Airport (COU) to Ft. Myers (RSW) flights

Calendar51Weekly Planes
Duration8h 31mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Sanibel Island.ExpandLaunch map view
  • Distance: 1,087.2 mi
  • Duration: 6h 31m

What companies run services between Jefferson City, MO, USA and Sanibel Island, FL, USA?

American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a vehicle from Jefferson City to Sanibel Island via Jefferson City, St Louis Bus Station, Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 31h 47m.

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