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How to get fromJefferson City to Sikestonby train, bus, taxi, car, or plane

Find Transport to Sikeston

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There are 5 ways to get from Jefferson City to Sikeston by train, bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus, taxi

    best
    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    6h 13m
    $147–235

  2. Drive 232.5 mi

    cheapest
    1. Drive from Jefferson City to Sikestoncar car 232.5 mi
    4h 36m
    $43–62

  3. Fly to Barkley Regional Airport, drive

    1. Fly from Columbia Regional Airport (COU) to Barkley Regional Airport (PAH)plane plane COU - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    8h 30m
    $162–482

  4. Bus, taxi

    1. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 23m
    $143–220

  5. Fly to Williamson County Regional Airport, bus

    1. Fly from Columbia Regional Airport (COU) to Williamson County Regional Airport (MWA)plane plane COU - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    7h 9m
    $230–668

Columbia Regional Airport (COU) to Barkley Regional Airport (PAH) flights

Calendar14Weekly Planes
Duration7h 2mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Sikeston.ExpandLaunch map view
  • Distance: 268 mi
  • Duration: 6h 13m

What companies run services between Jefferson City, MO, USA and Sikeston, MO, USA?

There is no direct connection from Jefferson City to Sikeston. However, you can take the train to St. Louis, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston. Alternatively, you can drive from Jefferson City to Sikeston in around 4h 36m.

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