Rome2Rio

How to get fromJefferson City to Tupeloby train, bus, car, shuttle, plane, or bus (Greyhound, Flixbus)

Find Transport to Tupelo

See all options

There are 5 ways to get from Jefferson City to Tupelo by train, bus, car, shuttle, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    11h 52m
    $96–184

  2. Drive  434.6 mi

    cheapest
    1. Drive from Jefferson City to Tupelocar car 434.6 mi
    8h 2m
    $80–115

  3. Shuttle, fly to Jonesboro Municipal Airport, bus

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    3. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    10h
    $303–675

  4. Bus

    1. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    13h 3m
    $101–169

  5. Shuttle, fly to Hartsfield-Jackson Atlanta International Airport, bus

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane STL - ATL
    3. Take the bus from Atlanta Bus Station to Tupelobus bus
    11h 48m
    $276–783

Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR) flights

Calendar6Weekly Planes
Duration1h 31mAverage Duration
Ticket$123Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Jefferson City to Tupelo.ExpandLaunch map view
  • Distance: 516.7 mi
  • Duration: 11h 52m

What companies run services between Jefferson City, MO, USA and Tupelo, MS, USA?

You can take a vehicle from Jefferson City to Tupelo via Jefferson City, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 13h 3m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There