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How to get fromJefferson City to Tupeloby train, bus, car, plane, bus (Greyhound, Flixbus), or shuttle

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There are 7 ways to get from Jefferson City to Tupelo by train, bus, car, plane, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Jefferson City Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    11h 2m
    $111–213

  2. Drive 434.6 mi

    cheapest
    1. Drive from Jefferson City to Tupelocar car 434.6 mi
    8h 2m
    $80–115

  3. Fly Columbia Regional Airport to Tupelo Regional Airport

    1. Fly from Columbia Regional Airport (COU) to Tupelo Regional Airport (TUP)plane plane COU - TUP
    7h 31m
    $186–555

  4. Bus

    1. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    12h 13m
    $125–214

  5. Shuttle to Lambert–St. Louis International Airport, fly to Tupelo Regional Airport

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Tupelo Regional Airport (TUP)plane plane STL - TUP
    8h 48m
    $226–614

  6. Drive to Waynesville-St. Robert Regional Airport, fly to Tupelo Regional Airport

    1. Drive from Jefferson City to Waynesville-St. Robert Regional Airport (TBN)car car
    2. Fly from Waynesville-St. Robert Regional Airport (TBN) to Tupelo Regional Airport (TUP)plane plane TBN - TUP
    8h 24m
    $168–639

  7. Shuttle to Lambert–St. Louis International Airport, fly to Jonesboro Municipal Airport, bus

    1. Take a shuttle bus from Jefferson City, Missouri to St Louis International Airportshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    3. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    9h 55m
    $339–731

Columbia Regional Airport (COU) to Tupelo Regional Airport (TUP) flights

Calendar9Weekly Planes
Duration8h 27mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Jefferson City to Tupelo.ExpandLaunch map view
  • Distance: 515.3 mi
  • Duration: 11h 2m

What companies run services between Jefferson City, MO, USA and Tupelo, MS, USA?

American Airlines, Corporate Flight Management Inc, and United Airlines fly from Columbia Regional Airport (COU) to Tupelo Regional Airport (TUP) once daily. Alternatively, you can take a vehicle from Jefferson City to Tupelo via Jefferson City, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 12h 13m.

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