There are 3 ways to get from Jeffersonville to St. Louis by bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Louisville, KY to Evansville, INbus Louisville
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus Greyhound US0186 / ...
8h 17m$63–178Drive 260.5 mi
cheapest- Drive from Jeffersonville to St. Louiscar 260.5 mi
4h 22m$48–69Fly
- Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane SDF - STL
6h 41m$101–659
Jeffersonville to St. Louis by bus and foot
Comparing Your Travel Options
The cheapest way to get from Jeffersonville to St. Louis is to drive which costs $45 - $70 and takes 4h 22m.
The fastest way to get from Jeffersonville to St. Louis is to drive which takes 4h 22m and costs $45 - $70.
No, there is no direct bus from Jeffersonville to St. Louis station. However, there are services departing from Court @ Spring and arriving at St Louis Bus Station via W Jefferson @ S 6th, Louisville, KY and Evansville Bus Station. The journey, including transfers, takes approximately 8h 17m.
The distance between Jeffersonville and St. Louis is 292 miles. The road distance is 262 miles.
The best way to get from Jeffersonville to St. Louis without a car is to bus which takes 8h 17m and costs $60 - $180.
It takes approximately 8h 17m to get from Jeffersonville to St. Louis, including transfers.
Jeffersonville to St. Louis bus services, operated by Miller Transportation, depart from Louisville, KY station.
The best way to get from Jeffersonville to St. Louis is to bus which takes 8h 17m and costs $60 - $180. Alternatively, you can fly, which costs $100 - $700 and takes 6h 41m.
Jeffersonville to St. Louis bus services, operated by Miller Transportation, arrive at Evansville, IN station.
St. Louis is 1h behind Jeffersonville. It is currently 1:43 PM in Jeffersonville and 12:43 PM in St. Louis.
What companies run services between Jeffersonville, IN, USA and St. Louis, MO, USA?
You can take a bus from Court @ Spring to St Louis Bus Station via W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, KY, and Evansville Bus Station in around 8h 17m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL) hourly.
- Website
- southwest.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $110–650
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 5h 25m
- When
- Tuesday to Friday
- Estimated price
- $95–650
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
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Booking & Getting There
Yes, the driving distance between Jeffersonville to St. Louis is 262 miles. It takes approximately 4h 22m to drive from Jeffersonville to St. Louis.
There are 559+ hotels available in St. Louis.