What is the cheapest way to get from Jeffersonville to St. Louis?

The cheapest way to get from Jeffersonville to St. Louis is to drive which costs $45 - $70 and takes 4h 22m.

What is the fastest way to get from Jeffersonville to St. Louis?

The fastest way to get from Jeffersonville to St. Louis is to drive which takes 4h 22m and costs $45 - $70.

Is there a direct bus between Jeffersonville and St. Louis?

No, there is no direct bus from Jeffersonville to St. Louis station. However, there are services departing from Court @ Spring and arriving at St Louis Bus Station via W Jefferson @ S 6th, Louisville and Evansville Bus Station. The journey, including transfers, takes approximately 8h 18m.

How far is it from Jeffersonville to St. Louis?

The distance between Jeffersonville and St. Louis is 292 miles. The road distance is 262 miles.

How do I travel from Jeffersonville to St. Louis without a car?

The best way to get from Jeffersonville to St. Louis without a car is to bus which takes 8h 18m and costs $80 - $130.

How long does it take to get from Jeffersonville to St. Louis?

It takes approximately 8h 18m to get from Jeffersonville to St. Louis, including transfers.

Where do I catch the Jeffersonville to St. Louis bus from?

Jeffersonville to St. Louis bus services, operated by Jefferson Lines, depart from Louisville station.

Bus or fly from Jeffersonville to St. Louis?

The best way to get from Jeffersonville to St. Louis is to bus which takes 8h 18m and costs $80 - $130. Alternatively, you can fly, which costs $100 - $650 and takes 6h 41m.

Where does the Jeffersonville to St. Louis bus arrive?

Jeffersonville to St. Louis bus services, operated by Jefferson Lines, arrive at Evansville station.

What is the time difference between Jeffersonville and St. Louis?

St. Louis is 1h behind Jeffersonville. It is currently 8:45 AM in Jeffersonville and 7:45 AM in St. Louis.

Can I drive from Jeffersonville to St. Louis?

Yes, the driving distance between Jeffersonville to St. Louis is 262 miles. It takes approximately 4h 22m to drive from Jeffersonville to St. Louis.

Where can I stay near St. Louis?

There are 520+ hotels available in St. Louis.

Jeffersonville to St. Louis - 3 ways to travel via bus, car, and plane

How to get fromJeffersonville to St. Louis

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There are 3 ways to get from Jeffersonville to St. Louis by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Louisville to Evansvillebus Mrt 361
2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus Greyhound US0186 / ...
8h 18m
$82–123
Drive 260.5 mi
cheapest
1. Drive from Jeffersonville to St. Louiscar 260.5 mi
4h 22m
$48–69
Fly
1. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane SDF - STL
6h 41m
$106–609

Jeffersonville to St. Louis by bus and foot

14Weekly Services

8h 18mAverage Duration

$82Cheapest Price

See schedules

Questions & Answers

Map of how to get from Jeffersonville to St. Louis.

Launch map view

Distance: 290.2 mi
Duration: 8h 18m

What companies run services between Jeffersonville, IN, USA and St. Louis, MO, USA?

You can take a bus from Court @ Spring to St Louis Bus Station via W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, Evansville, and Evansville Bus Station in around 8h 18m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL) hourly.

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How to get fromJeffersonville to St. Louisby bus (Greyhound), car, or plane

There are 3 ways to get from Jeffersonville to St. Louis by bus (Greyhound), car, or plane

Bus

Drive 260.5 mi

Fly