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How to get fromJohnson City to Des Moinesby car, plane, shuttle, bus, taxi, train, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Johnson City to Des Moines by car, plane, shuttle, bus, taxi, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mcghee Tyson Airport, fly

    best
    1. Drive from Johnson City to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    6h 44m
    $124–543

  2. Shuttle, bus

    1. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    2. Take the bus from Boone to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Chicagobus bus
    5. Take the bus from Chicago Bus Station to Des Moinesbus bus
    31h 43m
    $263–405

  3. Taxi, bus, train

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    3. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    4. Take the train from Roanoke to Charlottesvilletrain train
    5. Take the train from Charlottesville to Indianapolistrain train
    6. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    35h 26m
    $372–760

  4. Drive  872 mi

    1. Drive from Johnson City to Des Moinescar car 872 mi
    15h 38m
    $160–230

  5. Fly from Tri-Cities Regional Tn/Va Airport

    1. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Des Moines (DSM)plane plane TRI - DSM
    8h 14m
    $203–543

  6. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Johnson City to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    7h 3m
    $126–506

  7. Shuttle to Asheville Regional Airport, fly

    1. Take a shuttle bus from Black Bear Resort to Asheville Airportshuttle bus
    2. Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane plane AVL - DSM
    9h 6m
    $308–653

  8. Shuttle, bus to Charlotte Douglas International Airport, fly

    1. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    2. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    9h 25m
    $316–701

  9. Taxi, bus, train via Chicago

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    3. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    4. Take the train from Roanoke to Charlottesvilletrain train
    5. Take the train from Charlottesville to Chicago Union Stationtrain train
    6. Take the bus from Chicago Bus Station to Des Moinesbus bus
    37h 46m
    $407–895

  10. Bus

    1. Take the bus from Johnson City, TN to New York, NYbus bus Ny
    2. Take the bus from New York City Chinatown to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    40h 22m
    $323–464

Mcghee Tyson Airport (TYS) to Des Moines (DSM) flights

Calendar92Weekly Planes
Duration5h 37mAverage Duration
Ticket$89Cheapest Price
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Comparing Your Travel Options

Map of how to get from Johnson City to Des Moines.ExpandLaunch map view
  • Distance: 772.7 mi
  • Duration: 6h 44m

What companies run services between Johnson City, TN, USA and Des Moines, IA, USA?

Delta and American Airlines fly from Tri-Cities Regional Tn/Va Airport (TRI) to Des Moines (DSM) every 4 hours. Alternatively, you can take a vehicle from Johnson City to Des Moines via Johnson City, TN, New York City Chinatown, and Chicago Bus Station in around 40h 22m.

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