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How to get fromJohnson City to Mayo Clinicby plane, taxi, bus, train, car, or shuttle

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There are 8 ways to get from Johnson City to Mayo Clinic by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Tri-Cities Regional Tn/Va Airport to Rochester

    best
    1. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Rochester (RST)plane plane TRI - RST
    11h 8m
    $181–530

  2. Drive 931.5 mi

    cheapest
    1. Drive from Johnson City to Mayo Cliniccar car 931.5 mi
    16h 37m
    $170–246

  3. Taxi, bus

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Wytheville Rural King Parking Lotbus bus
    3. Take the bus from Wytheville to Columbus - Mound Stbus bus
    4. Take the bus from Columbus - Mound St to Chicagobus bus
    5. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    6. Take the bus from Madison to Rochesterbus bus
    29h 34m
    $256–430

  4. Taxi, bus, train

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Wytheville Rural King Parking Lotbus bus
    3. Take the bus from Wytheville to Ashlandbus bus
    4. Take the train from Ashland Amtrak Station to Chicago Union Stationtrain train
    5. Take the train from Chicago Union Station to Milwaukeetrain train
    6. Take the bus from Milwaukee to Rochesterbus bus
    30h 24m
    $387–675

  5. Drive to Mcghee Tyson Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Johnson City to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 34m
    $213–832

  6. Shuttle to Asheville Regional Airport, fly to Rochester

    1. Take a shuttle bus from Black Bear Resort to Asheville Airportshuttle bus
    2. Fly from Asheville Regional Airport (AVL) to Rochester (RST)plane plane AVL - RST
    11h 43m
    $291–660

  7. Shuttle to Asheville Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take a shuttle bus from Black Bear Resort to Asheville Airportshuttle bus
    2. Fly from Asheville Regional Airport (AVL) to Minneapolis–Saint Paul International Airport (MSP)plane plane AVL - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 51m
    $362–812

  8. Taxi, bus, train via Charlottesville

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    3. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    4. Take the train from Roanoke to Charlottesvilletrain train
    5. Take the train from Charlottesville to Chicago Union Stationtrain train
    6. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    7. Take the bus from Madison to Rochesterbus bus
    40h 13m
    $477–885

Tri-Cities Regional Tn/Va Airport (TRI) to Rochester (RST) flights

Calendar41Weekly Planes
Duration9h 8mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Johnson City to Mayo Clinic.ExpandLaunch map view
  • Distance: 798.9 mi
  • Duration: 11h 8m

What companies run services between Johnson City, TN, USA and Mayo Clinic, MN, USA?

American Airlines, United Airlines, and Delta fly from Tri-Cities Regional Tn/Va Airport (TRI) to Rochester (RST) every 4 hours.

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