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How to get fromJohnson City to St. Louisby car, plane, taxi, bus, train, or shuttle

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There are 8 ways to get from Johnson City to St. Louis by car, plane, taxi, bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mcghee Tyson Airport, fly

    best
    1. Drive from Johnson City to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    6h 3m
    $134–733

  2. Drive 551.2 mi

    cheapest
    1. Drive from Johnson City to St. Louiscar car 551.2 mi
    10h 27m
    $101–146

  3. Taxi, bus, train

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Wytheville Rural King Parking Lotbus bus
    3. Take the bus from Wytheville to Ashlandbus bus
    4. Take the train from Ashland Amtrak Station to Indianapolistrain train
    5. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    20h 32m
    $260–460

  4. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Johnson City to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    6h 31m
    $136–686

  5. Fly from Tri-Cities Regional Tn/Va Airport

    1. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Lambert–St. Louis International Airport (STL)plane plane TRI - STL
    7h 54m
    $213–663

  6. Shuttle to Asheville Regional Airport, fly

    1. Take a shuttle bus from Black Bear Resort to Asheville Airportshuttle bus
    2. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    8h 52m
    $313–763

  7. Taxi, bus

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    3. Take the bus from Exit 118 - Park and Ride to 3rd St Station Slip Dbus bus Swb
    4. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus
    5. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    21h 47m
    $227–355

  8. Taxi, bus via Carbondale

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    3. Take the bus from Exit 118 - Park and Ride to 3rd St Station Slip Dbus bus Swb
    4. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus
    5. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    6. Take the bus from Carbondale to St. Louisbus bus
    22h 2m
    $222–365

Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL) flights

Calendar125Weekly Planes
Duration4h 54mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from Johnson City to St. Louis.ExpandLaunch map view
  • Distance: 531.5 mi
  • Duration: 6h 3m

What companies run services between Johnson City, TN, USA and St. Louis, MO, USA?

American Airlines, Delta, and United Airlines fly from Tri-Cities Regional Tn/Va Airport (TRI) to Lambert–St. Louis International Airport (STL) every 3 hours.

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