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How to get fromJohnson City to St. Louisby car, plane, taxi, bus, or shuttle

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There are 7 ways to get from Johnson City to St. Louis by car, plane, taxi, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mcghee Tyson Airport, fly

    best
    1. Drive from Johnson City to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    7h 10m
    $102–580

  2. Drive  551.2 mi

    cheapest
    1. Drive from Johnson City to St. Louiscar car 551.2 mi
    10h 27m
    $91–132

  3. Taxi, bus

    1. Take the taxi from Johnson City to Bristol Exit 5 Park & Ride Lottaxi taxi
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    3. Take the bus from Exit 118 - Park and Ride to 3rd St Station Slip Dbus bus Swb
    4. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus
    5. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    21h 52m
    $233–337

  4. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Johnson City to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    6h 51m
    $113–582

  5. Fly from Tri-Cities Regional Tn/Va Airport

    1. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Lambert–St. Louis International Airport (STL)plane plane TRI - STL
    7h 43m
    $213–713

  6. Shuttle to Asheville Regional Airport, fly

    1. Take a shuttle bus from Black Bear Resort to Asheville Airportshuttle bus
    2. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    9h 8m
    $313–813

  7. Shuttle, bus

    1. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    2. Take the bus from Boone to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to St Louis Bus Stationbus bus
    26h 3m
    $258–360

Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL) flights

Calendar132Weekly Planes
Duration5h 15mAverage Duration
Ticket$84Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Johnson City to St. Louis.ExpandLaunch map view
  • Distance: 531.5 mi
  • Duration: 7h 10m

What companies run services between Johnson City, TN, USA and St. Louis, MO, USA?

Delta and American Airlines fly from Tri-Cities Regional Tn/Va Airport (TRI) to Lambert–St. Louis International Airport (STL) every 3 hours.

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