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How to get fromJoplin to Mayo Clinicby bus, car, shuttle, or plane

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There are 7 ways to get from Joplin to Mayo Clinic by bus, car, shuttle, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Joplin to Kansas Citybus bus
    2. Take the bus from Kansas City to Albert Leabus bus
    3. Take the bus from Albert Lea to Rochesterbus bus
    12h 53m

  2. Fly Joplin Regional Airport to Rochester

    cheapest
    1. Fly from Joplin Regional Airport (JLN) to Rochester (RST)plane plane JLN - RST
    9h 9m
    $88–405

  3. Drive 548.6 mi

    1. Drive from Joplin to Mayo Cliniccar car 548.6 mi
    9h 20m
    $101–145

  4. Shuttle to Northwest Arkansas Regional Airport, fly to Rochester

    1. Take a shuttle bus from Joplin, MO to Jane, MOshuttle bus
    2. Fly from Northwest Arkansas Regional Airport (XNA) to Rochester (RST)plane plane XNA - RST
    8h 19m
    $168–594

  5. Bus to Springfield-Branson National Airport, fly to Rochester

    1. Take the bus from Joplin Bus Station to Springfield CU Transit Centerbus bus
    2. Fly from Springfield-Branson National Airport (SGF) to Rochester (RST)plane plane SGF - RST
    9h 20m
    $101–430

  6. Shuttle to Northwest Arkansas Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take a shuttle bus from Joplin, MO to Jane, MOshuttle bus
    2. Fly from Northwest Arkansas Regional Airport (XNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane XNA - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 26m
    $235–746

  7. Bus to Kansas City, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Joplin to Kansas Citybus bus
    2. Fly from Kansas City (MCI) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCI - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 36m
    $696–1,063

Northwest Arkansas Regional Airport (XNA) to Rochester (RST) flights

Calendar39Weekly Planes
Duration5h 2mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Joplin to Mayo Clinic.ExpandLaunch map view
  • Distance: 565.1 mi
  • Duration: 12h 53m

What companies run services between Joplin, MO, USA and Mayo Clinic, MN, USA?

You can take a bus from Joplin to Mayo Clinic via Kansas City, Albert Lea, and Rochester in around 12h 53m. Alternatively, United Airlines, American Airlines, and Delta fly from Joplin Regional Airport (JLN) to Rochester (RST) 3 times a day.

Airlines
Bus operators

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