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How to get fromKalamazoo to Mayo Clinicby train, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Kalamazoo to Mayo Clinic by train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Madison

    best
    1. Take the train from Kalamazoo to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 2m
    $113–225

  2. Fly Kalamazoo-Battle Creek International Airport to Rochester

    cheapest
    1. Fly from Kalamazoo-Battle Creek International Airport (AZO) to Rochester (RST)plane plane AZO - RST
    9h 54m
    $52–382

  3. Train, bus

    1. Take the train from Kalamazoo to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    13h 20m
    $176–425

  4. Drive  490.9 mi

    1. Drive from Kalamazoo to Mayo Cliniccar car 490.9 mi
    8h 13m
    $90–130

  5. Bus

    1. Take the bus from Kalamazoo Bus Stop to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    12h 23m
    $107–160

  6. Train to Chicago O'Hare International Airport, fly to Rochester

    1. Take the train from Kalamazoo to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    7h 6m
    $84–413

  7. Bus to Gerald R. Ford International Airport, fly to Rochester

    1. Take the bus from Kalamazoo to Grand Rapidsbus bus
    2. Fly from Gerald R. Ford International Airport (GRR) to Rochester (RST)plane plane GRR - RST
    9h 6m
    $70–408

  8. Bus to Gerald R. Ford International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Kalamazoo to Grand Rapidsbus bus
    2. Fly from Gerald R. Ford International Airport (GRR) to Minneapolis–Saint Paul International Airport (MSP)plane plane GRR - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 42m
    $129–498

Kalamazoo to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration12h 2mAverage Duration
Ticket$113Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kalamazoo to Mayo Clinic.ExpandLaunch map view
  • Distance: 489.9 mi
  • Duration: 12h 2m

What companies run services between Kalamazoo, MI, USA and Mayo Clinic, MN, USA?

American Airlines and Delta fly from Kalamazoo-Battle Creek International Airport (AZO) to Rochester (RST) 5 times a day. Alternatively, you can take a bus from Kalamazoo Bus Stop to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 12h 23m.

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