There are 8 ways to get from Kalamazoo to Mayo Clinic by train, bus, car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Madison
best- Take the train from Kalamazoo to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
12h$150–245Fly Kalamazoo-Battle Creek International Airport to Rochester
cheapest- Fly from Kalamazoo-Battle Creek International Airport (AZO) to Rochester (RST)plane AZO - RST
8h 39m$58–382Train, bus
- Take the train from Kalamazoo to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
13h 18m$323–505Drive 490.9 mi
- Drive from Kalamazoo to Mayo Cliniccar 490.9 mi
8h 12m$84–122Bus
- Take the bus from Kalamazoo Bus Stop to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Rochesterbus
12h 21m$111–165Train to Chicago O'Hare International Airport, fly to Rochester
- Take the train from Kalamazoo to Chicago Union Stationtrain
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
7h 2m$116–423Bus to Gerald R. Ford International Airport, fly to Rochester
- Take the bus from Kalamazoo to Grand Rapidsbus
- Fly from Gerald R. Ford International Airport (GRR) to Rochester (RST)plane GRR - RST
9h 5m$70–408Bus to Gerald R. Ford International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Kalamazoo to Grand Rapidsbus
- Fly from Gerald R. Ford International Airport (GRR) to Minneapolis–Saint Paul International Airport (MSP)plane GRR - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 42m$134–518
Kalamazoo to Mayo Clinic by train, bus, and foot
Comparing Your Travel Options
The cheapest way to get from Kalamazoo to Mayo Clinic is to drive which costs $80 - $130 and takes 8h 12m.
The fastest way to get from Kalamazoo to Mayo Clinic is to train and fly which takes 7h 2m and costs $110 - $430.
No, there is no direct bus from Kalamazoo to Mayo Clinic. However, there are services departing from Kalamazoo Bus Stop and arriving at Rochester via Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 12h 21m.
The distance between Kalamazoo and Mayo Clinic is 493 miles. The road distance is 493.8 miles.
The best way to get from Kalamazoo to Mayo Clinic without a car is to train and bus via Madison which takes 12h and costs $150 - $250.
It takes approximately 12h to get from Kalamazoo to Mayo Clinic, including transfers.
Kalamazoo to Mayo Clinic bus services, operated by Greyhound USA, depart from Kalamazoo Bus Stop station.
The best way to get from Kalamazoo to Mayo Clinic is to fly which takes 8h 39m and costs $55 - $390. Alternatively, you can bus, which costs $110 - $170 and takes 12h 21m.
Kalamazoo to Mayo Clinic bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Kalamazoo to Mayo Clinic is 494 miles. It takes approximately 8h 12m to drive from Kalamazoo to Mayo Clinic.
What companies run services between Kalamazoo, MI, USA and Mayo Clinic, MN, USA?
American Airlines and Delta fly from Kalamazoo-Battle Creek International Airport (AZO) to Rochester (RST) 4 times a day. Alternatively, you can take a bus from Kalamazoo Bus Stop to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 12h 21m.
- Website
- delta.com
Flights from Kalamazoo-Battle Creek International Airport to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 8h 29m
- When
- Every day
- Estimated price
- $70–400
Flights from Gerald R. Ford International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $60–360
Flights from Gerald R. Ford International Airport to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $70–400
Flights from Gerald R. Ford International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $70–440
Flights from Gerald R. Ford International Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $85–490
- Website
- aa.com
Flights from Kalamazoo-Battle Creek International Airport to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $55–340
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $35–260
Flights from Gerald R. Ford International Airport to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $55–340
- Website
- southwest.com
Flights from Gerald R. Ford International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 55m
- When
- Saturday
- Estimated price
- $75–450
- Website
- united.com
Flights from Gerald R. Ford International Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $75–450
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kalamazoo to Chicago Union Station
- Ave. Duration
- 2h 16m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Kalamazoo to Chicago Union Station
- Ave. Duration
- 2h 16m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
Train from Kalamazoo to Chicago Union Station
- Ave. Duration
- 2h 16m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kalamazoo Bus Stop to Chicago Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $26–40
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $16–25
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–22
- Schedules at
- Flixbus USA
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Kalamazoo to Grand Rapids
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–24
- Website
- Indian Trails
Bus from Kalamazoo to Grand Rapids
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–24
- Website
- Indian Trails
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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