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How to get fromKansas City to Knoxvilleby plane, train, bus, car, or bus (Greyhound)

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There are 8 ways to get from Kansas City to Knoxville by plane, train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Kansas City (MCI) to Mcghee Tyson Airport (TYS)plane plane MCI - TYS
    5h 33m
    $235–1,020

  2. Drive 717 mi

    cheapest
    1. Drive from Kansas City to Knoxvillecar car 717 mi
    12h 34m
    $131–189

  3. Train, bus via Chicago

    1. Take the train from Kansas City to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    39h 29m
    $465–790

  4. Train, bus

    1. Take the train from Kansas City to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    42h 26m
    $635–1,190

  5. Fly to Nashville, drive

    1. Fly from Kansas City (MCI) to Nashville (BNA)plane plane MCI - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 15m
    $430–1,150

  6. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Kansas City (MCI) to Chattanooga Metropolitan Airport (CHA)plane plane MCI - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    7h 25m
    $228–1,128

  7. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    43h 22m
    $381–635

  8. Train, bus via Ossining

    1. Take the train from Kansas City to Naperville Amtrak Stationtrain train
    2. Take the train from Naperville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    43h 43m
    $586–1,104

Kansas City (MCI) to Mcghee Tyson Airport (TYS) flights

Calendar94Weekly Planes
Duration4h 46mAverage Duration
Ticket$183Cheapest Price
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Questions & Answers

Map of how to get from Kansas City to Knoxville.ExpandLaunch map view
  • Distance: 670.2 mi
  • Duration: 5h 33m

What companies run services between Kansas City, MO, USA and Knoxville, TN, USA?

Southwest Airlines, Delta, and two other airlines fly from Kansas City (MCI) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Knoxville via St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 43h 22m.

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