There are 7 ways to get from Karlovy Vary to Lyon by bus, plane, train (TGV), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Lyon–Saint Exupéry Airport
best- Take the bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2bus
- Fly from Václav Havel Airport Prague (PRG) to Lyon–Saint Exupéry Airport (LYS)plane PRG - LYS
6h 1m€74–231Train
- Take the train from Karlovy Vary to Chebtrain Re / ...
- Take the train from Cheb to Nuernberg Hbftrain
- Take the train from Nuernberg Hbf to Stuttgart Hbftrain Re
- Take the train from Hauptbahnhof to Strasbourg Bahnhoftrain 83
- Take the train from Strasbourg to Lyon Perrachetrain Tgv
14h 7m€171–311Train, bus
- Take the train from Karlovy Vary to Plzen-Jizni Predmestitrain Ic / ...
- Take the bus from Plzeň to Lyonbus N1315
18h 43m€104–160Drive 953.6 km
- Drive from Karlovy Vary to Lyoncar 953.6 km
9h 19m€181–261Bus, fly to Geneva International Airport, train
- Take the bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2bus
- Fly from Václav Havel Airport Prague (PRG) to Geneva International Airport (GVA)plane PRG - GVA
- Take the train from Bellegarde to Lyon Part Dieutrain
8h 46m€108–295Train via Lyon Part Dieu
- Take the train from Karlovy Vary to Chebtrain Re / ...
- Take the train from Cheb to Nuernberg Hbftrain
- Take the train from Nuernberg Hbf to Stuttgart Hbftrain Re
- Take the train from Hauptbahnhof to Strasbourg Bahnhoftrain 83
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
14h 14m€161–301Bus
- Take the bus from Karlovy Vary Terminal Bus Station to Prague Florenc Central Bus Stationbus RegioJet 141103
- Take the bus from Prague Florenc Central Bus Station to Lyon Perrache Bus Stationbus : Lyon - Prague Central Bus Station / ...
19h 5m€79–134
Karlovy Vary to Lyon by train
Comparing Your Travel Options
The cheapest way to get from Karlovy Vary to Lyon is to bus which costs €75 - €140 and takes 19h 5m.
The fastest way to get from Karlovy Vary to Lyon is to bus and fly which takes 6h 1m and costs €70 - €240.
No, there is no direct bus from Karlovy Vary station to Lyon station. However, there are services departing from Karlovy Vary Terminal Bus Station and arriving at Lyon Perrache Bus Station via Prague Florenc Central Bus Station. The journey, including transfers, takes approximately 19h 5m.
No, there is no direct train from Karlovy Vary to Lyon. However, there are services departing from Karlovy Vary and arriving at Lyon Perrache via Cheb, Nuernberg Hbf, Hauptbahnhof and Strasbourg. The journey, including transfers, takes approximately 14h 7m.
The distance between Karlovy Vary and Lyon is 979 km. The road distance is 953.6 km.
The best way to get from Karlovy Vary to Lyon without a car is to train which takes 14h 7m and costs €170 - €320.
It takes approximately 6h 1m to get from Karlovy Vary to Lyon, including transfers.
Karlovy Vary to Lyon bus services, operated by RegioJet, depart from Karlovy Vary Terminal Bus Station.
Karlovy Vary to Lyon train services, operated by České dráhy (ČD), depart from Karlovy Vary station.
The best way to get from Karlovy Vary to Lyon is to train which takes 14h 7m and costs €170 - €320. Alternatively, you can bus, which costs €75 - €140 and takes 19h 5m.
What companies run services between Karlovy Vary, Czechia and Lyon, France?
You can take a train from Karlovy Vary to Lyon Perrache via Cheb, Nuernberg Hbf, Stuttgart Hbf, Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 14h 7m. Alternatively, you can take a bus from Karlovy Vary Terminal Bus Station to Lyon Perrache Bus Station via Prague Florenc Central Bus Station in around 19h 5m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Tuesday, Wednesday, Thursday, Sunday, Monday, and Friday
- Estimated price
- €80–310
Flights from Václav Havel Airport Prague to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €80–240
Flights from Václav Havel Airport Prague to Geneva International Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–230
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Geneva International Airport via Zurich
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €80–240
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €45–170
Flights from Václav Havel Airport Prague to Geneva International Airport
- Ave. Duration
- 1h 35m
- When
- Friday and Sunday
- Estimated price
- €40–200
- Website
- volotea.com
Flights from Václav Havel Airport Prague to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 45m
- When
- Thursday
- Estimated price
- €23–140
- Website
- eurowings.com
Flights from Václav Havel Airport Prague to Geneva International Airport via Dusseldorf
- Ave. Duration
- 3h 50m
- When
- Wednesday
- Estimated price
- €65–270
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Karlovy Vary to Cheb
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- €4–7
- Website
- Czech Railways (ČD)
Train from Cheb to Nuernberg Hbf
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Czech Railways (ČD)
Train from Karlovy Vary to Plzen-Jizni Predmesti
- Ave. Duration
- 1h 57m
- Frequency
- Every 4 hours
- Estimated price
- €14–21
- Website
- Czech Railways (ČD)
Train from Karlovy Vary to Cheb
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- €4–7
- Website
- Czech Railways (ČD)
Train from Cheb to Nuernberg Hbf
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Czech Railways (ČD)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Cheb to Nuernberg Hbf
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €17–24
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Cheb to Nuernberg Hbf
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €17–24
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 27m
- Frequency
- Every 4 hours
- Estimated price
- €29–55
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €29–35
- 1st Class Ticket
- €35–55
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 27m
- Frequency
- Every 4 hours
- Estimated price
- €29–55
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €29–35
- 1st Class Ticket
- €35–55
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €26–40
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €26–40
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 16m
- Frequency
- 3 times a day
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 32m
- Frequency
- 5 times a day
- Estimated price
- €26–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 16m
- Frequency
- 3 times a day
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 32m
- Frequency
- 5 times a day
- Estimated price
- €26–55
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Lyon Perrache
- Ave. Duration
- 4h 5m
- Frequency
- Once a week
- Estimated price
- €100–160
- Website
- TGV inOui
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 12m
- Frequency
- 3 times a day
- Estimated price
- €100–150
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 12m
- Frequency
- 6 times a week
- Estimated price
- €22–40
- Website
- Oui.SNCF
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 20m
- Frequency
- 6 times a week
- Estimated price
- €90–150
- Website
- Oui.SNCF
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2
- Ave. Duration
- 1h 30m
- Frequency
- Every 2 hours
- Estimated price
- €7–13
- Website
- RegioJet
Bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2
- Ave. Duration
- 1h 30m
- Frequency
- Every 2 hours
- Estimated price
- €7–13
- Website
- RegioJet
Bus from Karlovy Vary Terminal Bus Station to Prague Florenc Central Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 2 hours
- Estimated price
- €8–14
- Website
- RegioJet
Bus from Prague Florenc Central Bus Station to Lyon Perrache Bus Station
- Ave. Duration
- 15h 50m
- Frequency
- Twice a week
- Estimated price
- €70–120
- Website
- RegioJet
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €10–16
- Website
- Flixbus
Bus from Plzeň to Lyon
- Ave. Duration
- 15h 35m
- Frequency
- Once daily
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €10–16
- Website
- Flixbus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Booking & Getting There
Karlovy Vary to Lyon bus services, operated by RegioJet, arrive at Prague Florenc Central Bus Station.
Karlovy Vary to Lyon train services, operated by České dráhy (ČD), arrive at Cheb station.
Yes, the driving distance between Karlovy Vary to Lyon is 954 km. It takes approximately 9h 19m to drive from Karlovy Vary to Lyon.
Book your Karlovy Vary to Lyon train tickets online with Omio.
Book your Karlovy Vary to Lyon bus tickets online with Omio and 12go.asia.
There are 3887+ hotels available in Lyon.






























