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How to get fromKarlovy Vary to Mannheimby train, bus, car, or plane

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There are 7 ways to get from Karlovy Vary to Mannheim by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlovy Vary to Chebtrain train Re / ...
    2. Take the train from Cheb to Nuernberg Hbftrain train
    3. Take the train from Nürnberg Hbf to Frankfurttrain train 41
    4. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train 12 / ...
    7h 11m
    €78–281
  2. Bus

    cheapest
    1. Take the bus from Karlovy Vary to Frankfurt central train stationbus bus 068 / ...
    2. Take the bus from Frankfurt central train station to Mannheim central bus stationbus bus FlixBus 108 / ...
    8h 32m
    €42–102
  3. Drive 412.5 km

    1. Drive from Karlovy Vary to Mannheimcar car 412.5 km
    3h 59m
    €64–92
  4. Bus to Václav Havel Airport Prague, fly, train

    1. Take the bus from Karlovy Vary Terminal Bus Station to Prague Airport Terminal 1/2bus bus
    2. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    3. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    5h 26m
    €72–217
  5. Train via Aschaffenburg

    1. Take the train from Karlovy Vary to Chebtrain train Re / ...
    2. Take the train from Cheb to Nuernberg Hbftrain train
    3. Take the train from Nürnberg Hbf to Aschaffenburg Hbftrain train 41 / ...
    4. Take the train from Aschaffenburg Hbf to Mannheim, Hauptbahnhoftrain train 12 / ...
    8h 3m
    €76–286
  6. Train, bus

    1. Take the train from Karlovy Vary to Chebtrain train Re / ...
    2. Take the train from Cheb to Nürnberg Hbftrain train
    3. Take the bus from Nuremberg - Bus Station to Heidelbergbus bus
    8h 34m
    €64–116
  7. Train, train to Nuremberg Airport, fly

    1. Take the train from Karlovy Vary to Chebtrain train
    2. Take the train from Cheb to Nuernberg Hbftrain train
    3. Fly from Nuremberg Airport (NUE) to Frankfurt (FRA)plane plane NUE - FRA
    4. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    6h 35m
    €124–250

Karlovy Vary to Mannheim by train

Calendar98Weekly Trains
Duration7h 11mAverage Duration
Ticket€78Cheapest Price
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Questions & Answers

What companies run services between Karlovy Vary, Czechia and Mannheim, Germany?

You can take a train from Karlovy Vary to Mannheim, Hauptbahnhof via Cheb, Nuernberg Hbf, Nürnberg Hbf, and Frankfurt in around 7h 11m. Alternatively, you can take a bus from Karlovy Vary to Mannheim central bus station via Frankfurt central train station in around 8h 32m.

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