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How to get fromKarlsruhe to Assisiby bus, train (Trenitalia), train, night train, car, or plane

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There are 13 ways to get from Karlsruhe to Assisi by bus, train (Trenitalia), train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    14h 50m
    €128–177

  2. Train to Strasbourg International Airport, fly to Fiumicino International Airport, train

    cheapest
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Fiumicino International Airport (FCO)plane plane SXB - FCO
    3. Take the train from Roma Termini to Assisitrain train
    9h 36m
    €82–307

  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Chiassotrain train Ec
    3. Take the train from Chiasso to Firenze S. M. N.train train Ec
    4. Take the train from Firenze S.M.N. to Assisitrain train
    16h 10m
    €161–379

  4. Train, night train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Assisitrain train
    20h 44m
    €106–286

  5. Drive  994.9 km

    1. Drive from Karlsruhe to Assisicar car 994.9 km
    9h 44m
    €162–233

  6. Train via Zurich

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Zürich HBtrain train Tgv / ...
    3. Take the train from Zürich HB to Como S. Giovannitrain train Ec
    4. Take the train from Como S. Giovanni to Firenze S. M. N.train train Ec
    5. Take the train from Firenze S.M.N. to Assisitrain train
    16h 38m
    €226–389

  7. Bus via Karlsruhe central train station

    1. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus bus N77
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    17h 50m
    €89–135

  8. Train to Stuttgart Airport, fly to Fiumicino International Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    3. Take the train from Roma Termini to Assisitrain train
    9h 54m
    €102–266

  9. Train, train to Frankfurt, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    4. Take the train from Firenze S.M.N. to Assisitrain train
    9h 50m
    €158–391

  10. Train, train to Frankfurt, fly to Fiumicino International Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    4. Take the train from Roma Termini to Assisitrain train
    10h 1m
    €83–245

  11. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Assisitrain train
    10h 23m
    €140–391

  12. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Assisitrain train
    11h 36m
    €171–440

  13. Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane plane ZRH - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Assisitrain train
    12h 9m
    €163–480

Karlsruhe to Assisi by train and bus

Calendar1Weekly Services
Duration16h 10mAverage Duration
Ticket€161Cheapest Price
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Map of how to get from Karlsruhe to Assisi.ExpandLaunch map view
  • Distance: 1,473.9 km
  • Duration: 14h 50m

What companies run services between Karlsruhe, Germany and Assisi, Italy?

You can take a bus from Karlsruhe Central Bus Station to Assisi via Florence Villa Constanza Bus Station in around 14h 50m. Alternatively, you can take a train from Karlsruhe Hauptbahnhof to Via San Francesco via Basel SBB, Chiasso, Firenze S. M. N., Firenze S.M.N., Assisi, and Assisi Stazione in around 16h 10m.

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