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How to get fromKarlsruhe to Assisiby train, bus, train (Trenitalia), car, or plane

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There are 13 ways to get from Karlsruhe to Assisi by train, bus, train (Trenitalia), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the bus from Basel to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    12h 18m
    €118–296

  2. Train to Strasbourg International Airport, fly to Fiumicino International Airport, train

    cheapest
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Fiumicino International Airport (FCO)plane plane SXB - FCO
    3. Take the train from Roma Termini to Assisitrain train
    9h 47m
    €81–308

  3. Train via Zurich

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Zürich HBtrain train Tgv / ...
    3. Take the train from Zürich HB to Chiassotrain train Ec / ...
    4. Take the train from Chiasso to Milano Lambratetrain train Ec
    5. Take the train from Milano Lambrate to Assisitrain train Ic
    16h 5m
    €195–451

  4. Drive  994.9 km

    1. Drive from Karlsruhe to Assisicar car 994.9 km
    9h 44m
    €162–233

  5. Train to Frankfurt, fly to Florence Peretola Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    3. Take the train from Firenze S.M.N. to Assisitrain train
    10h 5m
    €165–390

  6. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    14h 50m
    €129–178

  7. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Freiburg im Breisgau Train Stationtrain train 12 / ...
    2. Take the train from Freiburg im Breisgau Train Station to Chiassotrain train Ec
    3. Take the train from Chiasso to Milano Centraletrain train S11
    4. Take the train from Milano Centrale to Assisitrain train Ic
    16h 16m
    €214–439

  8. Bus via Karlsruhe central train station

    1. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus bus N77
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    17h 50m
    €95–141

  9. Train to Stuttgart Airport, fly to Fiumicino International Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    3. Take the train from Roma Termini to Assisitrain train
    9h 50m
    €107–279

  10. Train to Frankfurt, fly to Fiumicino International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    3. Take the train from Roma Termini to Assisitrain train
    9h 55m
    €89–224

  11. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    3. Take the train from Bologna Centrale to Assisitrain train
    10h 30m
    €148–368

  12. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Assisitrain train
    11h 58m
    €171–552

  13. Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane plane ZRH - BLQ
    4. Take the train from Bologna Centrale to Assisitrain train
    12h 28m
    €169–570

Karlsruhe to Assisi by train and bus

Calendar2Weekly Services
Duration16h 5mAverage Duration
Ticket€195Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Assisi.ExpandLaunch map view
  • Distance: 1,092.7 km
  • Duration: 12h 18m

What companies run services between Karlsruhe, Germany and Assisi, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Via San Francesco via Basel SBB, Zürich HB, Chiasso, Milano Lambrate, Assisi, and Assisi Stazione in around 16h 5m. Alternatively, you can take a bus from Karlsruhe Central Bus Station to Assisi via Florence Villa Constanza Bus Station in around 14h 50m.

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