There are 13 ways to get from Karlsruhe to Assisi by train, bus, train (Trenitalia), night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the bus from Basel to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
12h 17m€117–285Bus via Karlsruhe central train station
cheapest- Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus N77
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
17h 50m€81–130Train
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Chiassotrain Ec
- Take the train from Chiasso to Firenze S. M. N.train Ec
- Take the train from Firenze S.M.N. to Assisitrain
16h 7m€183–832Train, night train
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain Re
- Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain Nj
- Take the train from Verona Porta Nuova to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Assisitrain
21h 29m€109–291Drive 994.9 km
- Drive from Karlsruhe to Assisicar 994.9 km
9h 44m€157–227Bus
- Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
14h 52m€127–176Train to Frankfurt, fly to Florence Peretola Airport, train
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Assisitrain
9h 37m€166–410Train to Stuttgart Airport, fly to Fiumicino International Airport, train
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
- Take the train from Roma Termini to Assisitrain
9h 50m€105–265Train to Frankfurt, fly to Fiumicino International Airport, train
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
- Take the train from Roma Termini to Assisitrain
9h 42m€91–275Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
10h 2m€149–405Train, train to Zurich Airport, fly to Florence Peretola Airport
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Assisitrain
11h 24m€177–545Train, train to Zurich Airport, fly to Fiumicino International Airport
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Fiumicino International Airport (FCO)plane ZRH - FCO
- Take the train from Roma Termini to Assisitrain
11h 39m€117–440Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
11h 54m€170–580
Karlsruhe to Assisi by train and bus
Questions & Answers
The cheapest way to get from Karlsruhe to Assisi is to bus via Karlsruhe central train station which costs €80 - €130 and takes 17h 50m.
The fastest way to get from Karlsruhe to Assisi is to train and fly which takes 9h 37m and costs €160 - €410.
No, there is no direct bus from Karlsruhe station to Assisi. However, there are services departing from Karlsruhe Central Bus Station and arriving at Assisi via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 14h 52m.
No, there is no direct train from Karlsruhe to Assisi. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Assisi via Basel SBB, Chiasso and Firenze S.M.N.. The journey, including transfers, takes approximately 16h 7m.
The distance between Karlsruhe and Assisi is 1093 km. The road distance is 994.9 km.
The best way to get from Karlsruhe to Assisi without a car is to train and bus which takes 12h 17m and costs €110 - €290.
It takes approximately 12h 17m to get from Karlsruhe to Assisi, including transfers.
Karlsruhe to Assisi bus services, operated by Onebus, depart from Karlsruhe Central Bus Station.
Karlsruhe to Assisi train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Assisi is to train which takes 16h 7m and costs €180 - €850. Alternatively, you can bus, which costs €120 - €180 and takes 14h 52m.
What companies run services between Karlsruhe, Germany and Assisi, Italy?
You can take a train from Karlsruhe Hauptbahnhof to Via San Francesco via Basel SBB, Chiasso, Firenze S. M. N., Firenze S.M.N., Assisi, and Assisi Stazione in around 16h 7m. Alternatively, you can take a bus from Karlsruhe Central Bus Station to Assisi via Florence Villa Constanza Bus Station in around 14h 52m.
- Website
- ita-airways.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €120–600
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €70–150
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €70–120
Flights from Frankfurt to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–480
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €140–500
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €100–280
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €170–600
Flights from Zurich Airport to Fiumicino International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- €70–230
Flights from Zurich Airport to Fiumicino International Airport via Stuttgart Airport
- Ave. Duration
- 3h 20m
- When
- Tuesday
- Estimated price
- €60–230
Flights from Zurich Airport to Fiumicino International Airport via Bologna Guglielmo Marconi Airport
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €85–220
Flights from Zurich Airport to Fiumicino International Airport via Florence Peretola Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €85–220
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €85–420
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–140
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–140
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- €23–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- €23–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- €23–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–140
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–140
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–140
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Basel to Florence Villa Constanza Bus Station
- Ave. Duration
- 5h 46m
- Frequency
- Once a week
- Estimated price
- €80–120
- Website
- Onebus
Bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 11h 17m
- Frequency
- Once a week
- Estimated price
- €110–160
- Website
- Onebus
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More Questions & Answers
Karlsruhe to Assisi bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Karlsruhe to Assisi train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Karlsruhe to Assisi is 995 km. It takes approximately 9h 44m to drive from Karlsruhe to Assisi.
Book your Karlsruhe to Assisi bus tickets online with Omio.
There are 2432+ hotels available in Assisi.





