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How to get fromKarlsruhe to Assisiby train, bus, train (Trenitalia), night train, car, or plane

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There are 13 ways to get from Karlsruhe to Assisi by train, bus, train (Trenitalia), night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the bus from Basel to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    12h 18m
    €118–269

  2. Train, train to Frankfurt, fly to Fiumicino International Airport

    cheapest
    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    4. Take the train from Roma Termini to Assisitrain train
    9h 58m
    €86–262

  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Zürich HBtrain train Tgv / ...
    3. Take the train from Zürich HB to Chiassotrain train Ec / ...
    4. Take the train from Chiasso to Milano Lambratetrain train Ec
    5. Take the train from Milano Lambrate to Assisitrain train Ic
    16h 5m
    €191–605

  4. Train, night train

    1. Take the train from Karlsruhe Hauptbahnhof to Hauptbahnhoftrain train Re1
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Bologna centraletrain train
    4. Take the train from Bologna Centrale to Assisitrain train Ic
    21h 28m
    €102–279

  5. Drive  994.9 km

    1. Drive from Karlsruhe to Assisicar car 994.9 km
    9h 44m
    €158–228

  6. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    14h 52m
    €128–177

  7. Bus via Karlsruhe central train station

    1. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus bus N77
    2. Take the bus from Florence Villa Constanza Bus Station to Assisibus bus 529
    17h 50m
    €87–139

  8. Train to Stuttgart Airport, fly to Fiumicino International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    3. Take the train from Roma Termini to Assisitrain train
    9h 59m
    €104–250

  9. Train, train to Frankfurt, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    4. Take the train from Firenze S.M.N. to Assisitrain train
    9h 54m
    €161–403

  10. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Assisitrain train
    10h 26m
    €149–406

  11. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Assisitrain train
    11h 36m
    €177–533

  12. Train, train to Zurich Airport, fly to Fiumicino International Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Fiumicino International Airport (FCO)plane plane ZRH - FCO
    4. Take the train from Roma Termini to Assisitrain train
    11h 50m
    €117–422

  13. Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane plane ZRH - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Assisitrain train
    12h 12m
    €170–576

Karlsruhe to Assisi by train and bus

Calendar2Weekly Services
Duration16h 5mAverage Duration
Ticket€191Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Assisi.ExpandLaunch map view
  • Distance: 1,092.7 km
  • Duration: 12h 18m

What companies run services between Karlsruhe, Germany and Assisi, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Via San Francesco via Basel SBB, Zürich HB, Chiasso, Milano Lambrate, Assisi, and Assisi Stazione in around 16h 5m. Alternatively, you can take a bus from Karlsruhe Central Bus Station to Assisi via Florence Villa Constanza Bus Station in around 14h 52m.

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