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How to get fromKarlsruhe to Avignonby train (TGV), bus, car, train, or plane

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There are 7 ways to get from Karlsruhe to Avignon by train (TGV), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Avignon Tgvtrain train Tgv
    7h 14m
    €144–251

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Avignonbus bus FlixBus N1135 / ...
    11h 15m
    €61–105

  3. Drive  760.9 km

    1. Drive from Karlsruhe to Avignoncar car 760.9 km
    7h 33m
    €122–177

  4. Train to Strasbourg International Airport, fly to Marseille Provence Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Marseille Provence Airport (MRS)plane plane SXB - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    4h 38m
    €66–340

  5. Train, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Renens VDtrain train
    3. Take the train from Renens VD to Lancy-Pont-Rougetrain train
    4. Take the bus from Lancy Pont Rouge Gare-Etoile P+R to Gare Routierebus bus 272
    5. Take the train from Annecy to Avignon Centretrain train K21
    13h 4m
    €204–437

  6. Train to Frankfurt, fly to Marseille Provence Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Marseille Provence Airport (MRS)plane plane FRA - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    5h 52m
    €124–325

  7. Train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    3. Take the train from Lyon-Saint Exupery Tgv to Avignon Tgvtrain train
    5h 7m
    €140–419

Karlsruhe to Avignon by train

Calendar18Weekly Trains
Duration7h 14mAverage Duration
Ticket€144Cheapest Price
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Map of how to get from Karlsruhe to Avignon.ExpandLaunch map view
  • Distance: 813.3 km
  • Duration: 7h 14m

What companies run services between Karlsruhe, Germany and Avignon, France?

You can take a train from Karlsruhe Hauptbahnhof to Avignon Tgv via Strasbourg Bahnhof and Strasbourg in around 7h 14m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Avignon twice daily. Tickets cost €70–110 and the journey takes 10h 55m. BlaBlaCar Bus also services this route twice daily.

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