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How to get fromKarlsruhe to Avignonby train (TGV), bus, car, train, or plane

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There are 10 ways to get from Karlsruhe to Avignon by train (TGV), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Avignon Tgvtrain train Tgv
    7h 14m
    €153–244

  2. Train to Strasbourg International Airport, fly to Marseille Provence Airport, train

    cheapest
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Marseille Provence Airport (MRS)plane plane SXB - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    4h 23m
    €65–333

  3. Bus

    1. Take the bus from Karlsruhe central train station to Avignonbus bus FlixBus N1135 / ...
    11h 15m
    €66–108

  4. Drive  760.9 km

    1. Drive from Karlsruhe to Avignoncar car 760.9 km
    7h 33m
    €144–208

  5. Train via Lyon

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    3. Take the train from Lyon Part Dieu to Avignon Centretrain train Ter
    8h 50m
    €153–254

  6. Bus, train

    1. Take the bus from Karlsruhe - Central Station South Side to Marseille - Saint-Charles Bus Stationbus bus BlaBlaCar Bus
    2. Take the train from Marseille Saint-Charles to Avignon Centretrain train C7 / ...
    14h 42m
    €101–158

  7. Train to Frankfurt, fly to Marseille Provence Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Marseille Provence Airport (MRS)plane plane FRA - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    5h 42m
    €122–325

  8. Train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    3. Take the train from Lyon-Saint Exupery Tgv to Avignon Tgvtrain train
    4h 59m
    €139–402

  9. Train to Strasbourg International Airport, fly to Nice Côte D'Azur International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Nice Côte D'Azur International Airport (NCE)plane plane SXB - NCE
    3. Take the train from Nice-Saint-Augustin to Marseille-Saint-Charlestrain train
    4. Take the train from Marseille St Charles to Avignon Tgvtrain train
    7h 40m
    €117–342

  10. Train to Frankfurt, fly to Lyon–Saint Exupéry Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    3. Take the train from Lyon-Saint Exupery Tgv to Avignon Tgvtrain train
    6h 19m
    €156–424

Karlsruhe to Avignon by train

Calendar35Weekly Trains
Duration7h 14mAverage Duration
Ticket€153Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Avignon.ExpandLaunch map view
  • Distance: 813.3 km
  • Duration: 7h 14m

What companies run services between Karlsruhe, Germany and Avignon, France?

You can take a train from Karlsruhe Hauptbahnhof to Avignon Tgv via Strasbourg Bahnhof and Strasbourg in around 7h 14m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Avignon twice daily. Tickets cost €70–110 and the journey takes 10h 55m. BlaBlaCar Bus also services this route twice daily.

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