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How to get fromKarlsruhe to Brnoby train (TGV), bus, night train, train, car, or plane

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There are 11 ways to get from Karlsruhe to Brno by train (TGV), bus, night train, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the train from Hauptbahnhof to München Hbftrain train 11 / ...
    3. Take the train from Muenchen Hbf Gl.5-10 to Salzburg Hbftrain train Re / ...
    4. Take the train from Salzburg Hbf to Wien Hbftrain train Rjx / ...
    5. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train Rj / ...
    9h 24m
    Kč 2,334–7,076

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Mannheim central bus stationbus bus FlixBus 108 / ...
    2. Take the bus from Mannheim central bus station to Brnobus bus N1309
    12h 25m
    Kč 1,633–2,638

  3. Night train, train

    1. Take the nighttrain from Karlsruhe Hbf to Praha Hlavni Nadrazinighttrain night train En
    2. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train Rj / ...
    13h 3m
    Kč 3,871–7,462

  4. Drive  725.2 km

    1. Drive from Karlsruhe to Brnocar car 725.2 km
    6h 10m
    Kč 3,278–4,735

  5. Train, bus

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the bus from Stuttgart to Brno Hlavní Nádražíbus bus Ivano-Frankivsk
    14h 4m
    Kč 2,414–3,126

  6. Train to Stuttgart Airport, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane plane STR - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    6h 47m
    Kč 2,179–7,501

  7. Train to Frankfurt, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane plane FRA - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    6h 46m
    Kč 2,328–5,922

  8. Train to Frankfurt, fly to Václav Havel Airport Prague, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    3. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train
    7h 39m
    Kč 2,161–5,502

  9. Train to Basel, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Fly from Basel (BSL) to Vienna International Airport (VIE)plane plane BSL - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 53m
    Kč 2,664–10,742

  10. Train, train to Zurich Airport, fly to Vienna International Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Vienna International Airport (VIE)plane plane ZRH - VIE
    4. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    9h 4m
    Kč 3,727–11,026

  11. Train to Saint Gallen-Altenrhein Airport, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Konstanz Bahnhoftrain train
    2. Fly from Saint Gallen-Altenrhein Airport (ACH) to Vienna International Airport (VIE)plane plane ACH - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    10h
    Kč 9,568–15,654

Karlsruhe to Brno by train

Calendar185Weekly Trains
Duration9h 24mAverage Duration
TicketKč 2,334Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Brno.ExpandLaunch map view
  • Distance: 917.9 km
  • Duration: 9h 24m

What companies run services between Karlsruhe, Germany and Brno, Czechia?

You can take a train from Karlsruhe Hbf to Brno Hlavni Nadrazi via Stuttgart Hbf, Hauptbahnhof, München Hbf, Muenchen Hbf Gl.5-10, Salzburg Hbf, and Wien Hbf in around 9h 24m. Alternatively, you can take a bus from Karlsruhe central train station to Brno via Mannheim central bus station in around 12h 25m.

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