Rome2Rio

How to get fromKarlsruhe to Brnoby train (TGV), bus, night train, train, car, or plane

Find Transport to Brno

See all options

There are 9 ways to get from Karlsruhe to Brno by train (TGV), bus, night train, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the train from Hauptbahnhof to München Hbftrain train 11 / ...
    3. Take the train from Muenchen Hbf to Salzburg Hbftrain train Re / ...
    4. Take the train from Salzburg Hbf to Wien Hbftrain train Rjx / ...
    5. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train Rj / ...
    10h 8m
    Kč 2,497–8,900

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Mannheim central bus stationbus bus FlixBus 108 / ...
    2. Take the bus from Mannheim central bus station to Brnobus bus N1309
    12h 25m
    Kč 1,633–2,534

  3. Night train, train

    1. Take the nighttrain from Karlsruhe Hbf to Praha Hlavni Nadrazinighttrain night train En
    2. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train Re / ...
    13h 41m
    Kč 4,238–8,074

  4. Drive  725.1 km

    1. Drive from Karlsruhe to Brnocar car 725.1 km
    6h 9m
    Kč 2,802–4,047

  5. Train, bus

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the bus from Stuttgart to Brno Hlavní Nádražíbus bus Ivano-Frankivsk
    14h 4m
    Kč 2,527–3,950

  6. Train to Stuttgart Airport, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane plane STR - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 23m
    Kč 2,327–8,110

  7. Train to Frankfurt, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane plane FRA - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 23m
    Kč 2,367–6,098

  8. Train to Frankfurt, fly to Václav Havel Airport Prague, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    3. Take the train from Praha hl.n. to Brno hl.n.train train
    8h 29m
    Kč 2,210–4,528

  9. Train to Basel, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Fly from Basel (BSL) to Vienna International Airport (VIE)plane plane BSL - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    8h 30m
    Kč 2,551–11,935

Karlsruhe to Brno by train

Calendar93Weekly Trains
Duration10h 8mAverage Duration
TicketKč 2,497Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Karlsruhe to Brno.ExpandLaunch map view
  • Distance: 917.9 km
  • Duration: 10h 8m

What companies run services between Karlsruhe, Germany and Brno, Czechia?

You can take a train from Karlsruhe Hbf to Brno Hlavni Nadrazi via Stuttgart Hbf, Hauptbahnhof, München Hbf, Muenchen Hbf, Salzburg Hbf, and Wien Hbf in around 10h 8m. Alternatively, you can take a bus from Karlsruhe central train station to Brno via Mannheim central bus station in around 12h 25m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Czechia

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Booking & Getting There