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How to get fromKarlsruhe to Brnoby train (TGV), bus, night train, train, car, or plane

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There are 10 ways to get from Karlsruhe to Brno by train (TGV), bus, night train, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Re / ...
    2. Take the train from Stuttgart Hbf to Salzburg Hbftrain train 963 / ...
    3. Take the train from Salzburg Hbf to Wien Hbftrain train Rjx / ...
    4. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train Rj / ...
    10h 57m
    Kč 2,989–8,476

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Mannheim central bus stationbus bus FlixBus 108 / ...
    2. Take the bus from Mannheim central bus station to Brnobus bus N1309
    12h 25m
    Kč 1,629–2,532

  3. Night train, train

    1. Take the nighttrain from Karlsruhe Hbf to Praha Hlavni Nadrazinighttrain night train En
    2. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train Ic
    13h 4m
    Kč 4,394–8,397

  4. Drive  725.1 km

    1. Drive from Karlsruhe to Brnocar car 725.1 km
    6h 9m
    Kč 2,783–4,020

  5. Train, bus

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Re / ...
    2. Take the bus from Stuttgart to Brno Hlavní Nádražíbus bus Ivano-Frankivsk
    14h 21m
    Kč 2,509–3,726

  6. Train to Stuttgart Airport, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane plane STR - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 26m
    Kč 2,204–8,316

  7. Train to Frankfurt, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane plane FRA - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 8m
    Kč 2,409–5,878

  8. Train to Frankfurt, fly to Václav Havel Airport Prague, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    3. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train
    7h 40m
    Kč 2,242–5,558

  9. Train to Basel, fly to Vienna International Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Fly from Basel (BSL) to Vienna International Airport (VIE)plane plane BSL - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    8h 15m
    Kč 2,563–10,058

  10. Train, train to Zurich Airport, fly to Vienna International Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Vienna International Airport (VIE)plane plane ZRH - VIE
    4. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    9h 26m
    Kč 3,727–10,243

Karlsruhe to Brno by train

Calendar61Weekly Trains
Duration10h 57mAverage Duration
TicketKč 2,989Cheapest Price
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Map of how to get from Karlsruhe to Brno.ExpandLaunch map view
  • Distance: 919.4 km
  • Duration: 10h 57m

What companies run services between Karlsruhe, Germany and Brno, Czechia?

You can take a train from Karlsruhe Hbf to Brno Hlavni Nadrazi via Stuttgart Hbf, Salzburg Hbf, and Wien Hbf in around 10h 57m. Alternatively, you can take a bus from Karlsruhe central train station to Brno via Mannheim central bus station in around 12h 25m.

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