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How to get fromKarlsruhe to Brusselsby train (Eurostar), bus, car, train, or plane

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There are 11 ways to get from Karlsruhe to Brussels by train (Eurostar), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Cologne

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Köln Hbftrain train 43 / ...
    2. Take the train from Köln Hbf to Bruxelles Miditrain train 79
    4h 47m
    €96–250

  2. Bus via Strasbourg

    cheapest
    1. Take the bus from Karlsruhe central train station to Strasbourgbus bus FlixBus 108 / ...
    2. Take the bus from Strasbourg - L'Étoile Park Bus Station to Brussels - Midi Train Stationbus bus BlaBlaCar Bus
    7h 55m
    €33–60

  3. Bus

    1. Take the bus from Karlsruhe central train station to Brussels-North train stationbus bus N136 / ...
    7h 35m
    €40–65

  4. Drive  437.9 km

    1. Drive from Karlsruhe to Brusselscar car 437.9 km
    4h 36m
    €70–101

  5. Train, train to Frankfurt, fly to Brussels Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Brussels Airport (BRU)plane plane FRA - BRU
    4h 30m
    €99–295

  6. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Brussels-Nordtrain train 79
    4h 55m
    €93–201

  7. Train, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhoftrain train Re6
    2. Take the train from Neustadt, Hauptbahnhof to Trier, Hauptbahnhoftrain train Re1
    3. Take the bus from Trier, Balduinsbrunnen/Hbf to Luxembourgbus bus L32 / ...
    4. Take the train from Luxembourg to Bruxelles-Centraltrain train Ic / ...
    9h 35m

  8. Train to Stuttgart Airport, fly to Brussels Airport

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Brussels Airport (BRU)plane plane STR - BRU
    6h 43m
    €138–386

  9. Train, train to Zurich Airport, fly to Brussels Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Brussels Airport (BRU)plane plane ZRH - BRU
    6h 56m
    €142–354

  10. Train to Stuttgart Airport, fly to Amsterdam Airport Schiphol, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Amsterdam Airport Schiphol (AMS)plane plane STR - AMS
    3. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    6h 49m
    €216–532

  11. Train, train to Frankfurt, fly to Amsterdam Airport Schiphol

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Amsterdam Airport Schiphol (AMS)plane plane FRA - AMS
    4. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    6h 26m
    €197–481

Karlsruhe to Brussels by train

Calendar53Weekly Trains
Duration4h 47mAverage Duration
Ticket€96Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Brussels.ExpandLaunch map view
  • Distance: 519.4 km
  • Duration: 4h 47m

What companies run services between Karlsruhe, Germany and Brussels, Belgium?

You can take a train from Karlsruhe Hauptbahnhof to Bruxelles Midi via Köln Hbf in around 4h 47m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Brussels-North train station once daily. Tickets cost €40–65 and the journey takes 7h 35m.

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