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How to get fromKarlsruhe to Brusselsby train (Eurostar), bus, car, train, or plane

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There are 9 ways to get from Karlsruhe to Brussels by train (Eurostar), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Köln Hbftrain train 43 / ...
    2. Take the train from Koeln Hbf to Brussel-Zuid / Bruxelles-Miditrain train Thalys
    5h 2m
    €120–351

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Brussels-North train stationbus bus N136 / ...
    7h 35m
    €45–75

  3. Drive 437.9 km

    1. Drive from Karlsruhe to Brusselscar car 437.9 km
    4h 35m
    €68–98

  4. Train to Frankfurt, fly to Brussels Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Brussels Airport (BRU)plane plane FRA - BRU
    4h 26m
    €101–335

  5. Train via Bruxelles Midi

    1. Take the train from Karlsruhe Hauptbahnhof to Köln Hbftrain train 43 / ...
    2. Take the train from Köln Hbf to Bruxelles Miditrain train 79
    5h 11m
    €90–401

  6. Train to Stuttgart Airport, fly to Brussels Airport

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Brussels Airport (BRU)plane plane STR - BRU
    6h 36m
    €120–322

  7. Train to Frankfurt, fly to Amsterdam Airport Schiphol, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Amsterdam Airport Schiphol (AMS)plane plane FRA - AMS
    3. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    6h 21m
    €199–481

  8. Train to Stuttgart Airport, fly to Amsterdam Airport Schiphol, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Amsterdam Airport Schiphol (AMS)plane plane STR - AMS
    3. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    6h 40m
    €203–438

  9. Train, train to Zurich Airport, fly to Brussels Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Brussels Airport (BRU)plane plane ZRH - BRU
    6h 58m
    €142–485

Karlsruhe to Brussels by train

Calendar72Weekly Trains
Duration5h 2mAverage Duration
Ticket€120Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Brussels.ExpandLaunch map view
  • Distance: 519.5 km
  • Duration: 5h 2m

What companies run services between Karlsruhe, Germany and Brussels, Belgium?

You can take a train from Karlsruhe Hauptbahnhof to Brussel-Zuid / Bruxelles-Midi via Koeln Hbf in around 5h 2m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Brussels-North train station once daily. Tickets cost €45–75 and the journey takes 7h 35m.

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Want to know more about travelling around Belgium

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