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How to get fromKarlsruhe to Grenobleby train (TGV), bus, car, train, plane, or night train

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There are 9 ways to get from Karlsruhe to Grenoble by train (TGV), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    3. Take the train from Lyon Part Dieu to Grenobletrain train Ter
    7h 47m
    €122–221

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Lyonbus bus FlixBus N1135 / ...
    2. Take the bus from Lyon to Grenoblebus bus S1777 / ...
    9h 34m
    €50–88

  3. Drive  578.7 km

    1. Drive from Karlsruhe to Grenoblecar car 578.7 km
    5h 39m
    €93–134

  4. Train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    3. Take the train from Lyon-Saint Exupery Tgv to Grenobletrain train
    5h 20m
    €135–389

  5. Train, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Renens VDtrain train
    3. Take the train from Renens VD to Genève-Aéroporttrain train Ic1 / ...
    4. Take the bus from Geneva - Airport Bus Station to Grenoble - Bus Stationbus bus
    8h 51m
    €115–308

  6. Night train, bus, train

    1. Take the nighttrain from Karlsruhe Hbf to Basel Sbbnighttrain night train Nj
    2. Take the bus from Basel SBB to Annecybus bus
    3. Take the train from Annecy to Grenobletrain train K21
    10h 26m
    €76–175

  7. Train to Frankfurt, fly to Lyon–Saint Exupéry Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    3. Take the train from Lyon-Saint Exupery Tgv to Grenobletrain train
    6h 34m
    €153–395

  8. Train to Frankfurt, fly to Geneva International Airport, bus, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane plane FRA - GVA
    3. Take the bus from Geneva - Airport Bus Station to Chambéry - Bus Stationbus bus
    4. Take the train from Chambery Challes Les Eaux to Grenobletrain train
    7h 24m
    €151–346

  9. Train, train to Zurich Airport, fly to Geneva International Airport, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Geneva International Airport (GVA)plane plane ZRH - GVA
    4. Take the bus from Geneva - Airport Bus Station to Chambéry - Bus Stationbus bus
    5. Take the train from Chambery Challes Les Eaux to Grenobletrain train
    8h 21m
    €182–588

Karlsruhe to Grenoble by train

Calendar32Weekly Trains
Duration7h 47mAverage Duration
Ticket€122Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Grenoble.ExpandLaunch map view
  • Distance: 717.5 km
  • Duration: 7h 47m

What companies run services between Karlsruhe, Germany and Grenoble, France?

You can take a train from Karlsruhe Hauptbahnhof to Grenoble via Strasbourg Bahnhof, Strasbourg, and Lyon Part Dieu in around 7h 47m. Alternatively, you can take a bus from Karlsruhe central train station to Grenoble via Lyon in around 9h 34m.

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