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How to get fromKarlsruhe to Ispraby train, bus, night train, car, or plane

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There are 8 ways to get from Karlsruhe to Ispra by train, bus, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Bellinzonatrain train Ec
    3. Take the train from Bellinzona to Varesetrain train S50
    8h 16m
    €45–415

  2. Bus

    1. Take the bus from Karlsruhe central train station to Como Grandatebus bus FlixBus 024
    12h 28m
    €50–81

  3. Night train, train

    1. Take the night train from Karlsruhe Hbf to Zuerich Hbnighttrain night train Nj
    2. Take the train from Zürich HB to Bellinzonatrain train Ec / ...
    3. Take the train from Bellinzona to Varesetrain train S50
    9h 10m
    €75–170

  4. Drive 490.8 km

    1. Drive from Karlsruhe to Ispracar car 490.8 km
    5h 11m
    €77–112

  5. Train to Frankfurt, fly to Milano Malpensa Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    3. Take the train from Malpensa Aeroporto T1 to Varesetrain train
    6h 34m
    €88–331

  6. Train to Stuttgart Airport, fly to Milano Malpensa Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane plane STR - MXP
    3. Take the train from Malpensa Aeroporto T1 to Varesetrain train
    6h 38m
    €87–278

  7. Train to Frankfurt, fly to Milan Linate Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    3. Take the train from Milano Dateo to Varesetrain train
    7h 36m
    €70–250

  8. Train, train to Zurich Airport, fly to Milano Malpensa Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Milano Malpensa Airport (MXP)plane plane ZRH - MXP
    4. Take the train from Malpensa Aeroporto T1 to Varesetrain train
    7h 45m
    €129–480

Karlsruhe to Ispra by train and bus

Calendar118Weekly Services
Duration8h 16mAverage Duration
Ticket€45Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Ispra.ExpandLaunch map view
  • Distance: 509.2 km
  • Duration: 8h 16m

What companies run services between Karlsruhe, Germany and Ispra, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Ispra, Mazzini 59,banca via Basel SBB, Bellinzona, Varese, and Varese, V. Veneto 9 in around 8h 16m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Como Grandate 6 times a week. Tickets cost €45–80 and the journey takes 9h 5m.

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