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How to get fromKarlsruhe to Italyby train, plane, bus, night train, or car

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There are 11 ways to get from Karlsruhe to Italy by train, plane, bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Stuttgart Airport, fly to Milan Linate Airport

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Milan Linate Airport (LIN)plane plane STR - LIN
    4h 50m
    €117–355

  2. Train to Frankfurt, fly to Milan Linate Airport

    cheapest
    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    4h 33m
    €60–201

  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Roma Terminitrain train
    11h 1m
    €136–351

  4. Bus via Balsamo Crivelli

    1. Take the bus from Karlsruhe Central Bus Station to Roma Prenestina A1bus bus
    14h 40m
    €131–184

  5. Train, night train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Re / ...
    2. Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Roma Terminitrain train Fr
    17h 57m
    €108–300

  6. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4h 46m
    €119–308

  7. Train to Stuttgart Airport, fly to Milano Malpensa Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane plane STR - MXP
    3. Take the train from Malpensa Aeroporto T1 to Milano Cadornatrain train
    5h 28m
    €85–268

  8. Train to Frankfurt, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    5h 4m
    €146–340

  9. Train to Stuttgart Airport, fly to Fiumicino International Airport

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    5h 43m
    €84–218

  10. Bus

    1. Take the bus from Karlsruhe central train station to Roma, Autostazione Tiburtinabus bus N77
    18h 8m
    €103–160

  11. Drive  1,097.7 km

    1. Drive from Karlsruhe to Romecar car 1,097.7 km
    10h 27m
    €178–256

Karlsruhe to Italy by train and night train

Calendar7Weekly Services
Duration17h 57mAverage Duration
Ticket€108Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Italy.ExpandLaunch map view
  • Distance: 465.4 km
  • Duration: 4h 50m

What companies run services between Karlsruhe, Germany and Italy?

You can take a train from Karlsruhe Hauptbahnhof to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 11h 1m. Alternatively, Onebus operates a bus from Karlsruhe Central Bus Station to Roma Prenestina A1 once a week. Tickets cost €130–180 and the journey takes 13h 45m.

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Want to know more about travelling around Italy

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