There are 11 ways to get from Karlsruhe to Italy by train, plane, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, train to Frankfurt, fly to Milan Linate Airport
best- Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
4h 38m€50–190Train
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
11h€140–369Bus via Balsamo Crivelli
- Take the bus from Karlsruhe Central Bus Station to Roma Prenestina A1bus
14h 43m€131–184Train, night train
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain Ice / ...
- Take the nighttrain from Stuttgart Hbf to Padovanighttrain Nj
- Take the train from Padova to Roma Terminitrain Fr
19h 35m€108–288Train to Stuttgart Airport, fly to Milano Malpensa Airport, train
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane STR - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Cadornatrain
5h 20m€80–217Train to Stuttgart Airport, fly to Naples Airport
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Naples Airport (NAP)plane STR - NAP
5h 38m€91–226Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport
- Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
4h 56m€114–297Train, train to Frankfurt, fly to Florence Peretola Airport
- Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
5h 15m€136–329Train, train to Frankfurt, fly to Turin Caselle Airport
- Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Turin Caselle Airport (TRN)plane FRA - TRN
5h 27m€107–311Bus
- Take the bus from Karlsruhe central train station to Roma, Autostazione Tiburtinabus N77
18h 8m€100–156Drive 1,097.7 km
- Drive from Karlsruhe to Romecar 1,097.7 km
10h 27m€175–253
Karlsruhe to Italy by train
Questions & Answers
The cheapest way to get from Karlsruhe to Italy is to train and fly which costs €45 - €190 and takes 4h 38m.
The fastest way to get from Karlsruhe to Italy is to train and fly which takes 4h 38m and costs €45 - €190.
No, there is no direct bus from Karlsruhe station to Italy. However, there are services departing from Karlsruhe Central Bus Station and arriving at Croce Rossa via Balsamo Crivelli. The journey, including transfers, takes approximately 14h 43m.
No, there is no direct train from Karlsruhe to Italy. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Roma Termini via Basel SBB, Lugano and Milano Centrale. The journey, including transfers, takes approximately 11h.
The distance between Karlsruhe and Italy is 652 km. The road distance is 1097.7 km.
The best way to get from Karlsruhe to Italy without a car is to train which takes 11h and costs €140 - €370.
It takes approximately 4h 38m to get from Karlsruhe to Italy, including transfers.
Karlsruhe to Italy bus services, operated by Onebus, depart from Karlsruhe Central Bus Station.
Karlsruhe to Italy train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Italy is to train which takes 11h and costs €140 - €370. Alternatively, you can bus via Balsamo Crivelli, which costs €130 - €190 and takes 14h 43m.
What companies run services between Karlsruhe, Germany and Italy?
You can take a train from Karlsruhe Hauptbahnhof to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 11h. Alternatively, Onebus operates a bus from Karlsruhe Central Bus Station to Roma Prenestina A1 once a week. Tickets cost €130–180 and the journey takes 13h 48m.
- Website
- lufthansa.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–500
Flights from Frankfurt to Milan Linate Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €50–350
Flights from Stuttgart Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €140–470
Flights from Stuttgart Airport to Naples Airport via Munich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €55–310
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €150–550
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €110–600
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €180–650
Flights from Frankfurt to Turin Caselle Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €95–550
Flights from Frankfurt to Turin Caselle Airport via Munich
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €95–600
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €35–70
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Karlsruhe Central Bus Station to Roma Prenestina A1
- Ave. Duration
- 13h 48m
- Frequency
- Once a week
- Estimated price
- €130–180
- Website
- Onebus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Getting to Milan from the airport
Read the travel guide
More Questions & Answers
Karlsruhe to Italy bus services, operated by Onebus, arrive at Roma Prenestina A1 station.
Karlsruhe to Italy train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Karlsruhe to Italy is 1098 km. It takes approximately 10h 27m to drive from Karlsruhe to Italy.
Book your Karlsruhe to Italy train tickets online with Omio.
There are 21449+ hotels available in Italy.





