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How to get fromKarlsruhe to Luganoby train, bus, car, or plane

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There are 8 ways to get from Karlsruhe to Lugano by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ic21 / ...
    5h 42m
    CHF 38–291

  2. Bus

    1. Take the bus from Karlsruhe central train station to Luganobus bus FlixBus 024 / ...
    6h 45m
    CHF 40–60

  3. Drive  453.8 km

    1. Drive from Karlsruhe to Luganocar car 453.8 km
    4h 24m
    CHF 87–126

  4. Train to Stuttgart Airport, fly to Zurich Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane plane STR - ZRH
    3. Take the train from Zürich HB to Luganotrain train
    5h 37m
    CHF 168–469

  5. Train, bus

    1. Take the train from Karlsruhe Hbf to Zuerich Hbtrain train Ec
    2. Take the bus from Zürich Hbf to Lugano Stazionebus bus
    7h 27m
    CHF 73–77

  6. Train to Frankfurt, fly to Milano Malpensa Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    3. Take the train from Malpensa Aeroporto T1 to Luganotrain train
    6h 39m
    CHF 81–220

  7. Train to Frankfurt, fly to Milan Linate Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    3. Take the train from Monza to Luganotrain train
    6h 50m
    CHF 57–193

  8. Train to Stuttgart Airport, fly to Milan Linate Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Milan Linate Airport (LIN)plane plane STR - LIN
    3. Take the train from Monza to Luganotrain train
    6h 51m
    CHF 116–366

Karlsruhe to Lugano by train

Calendar76Weekly Trains
Duration5h 42mAverage Duration
TicketCHF 38Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Lugano.ExpandLaunch map view
  • Distance: 445.9 km
  • Duration: 5h 42m

What companies run services between Karlsruhe, Germany and Lugano, Switzerland?

You can take a train from Karlsruhe Hauptbahnhof to Lugano via Basel SBB in around 5h 42m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Lugano twice daily. Tickets cost CHF 40–60 and the journey takes 6h 45m.

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