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How to get fromKarlsruhe to Lyonby train (TGV), bus, car, train, or plane

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There are 8 ways to get from Karlsruhe to Lyon by train (TGV), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Lyon Perrachetrain train Tgv
    5h 48m
    €113–188

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Lyonbus bus N1315 / ...
    8h 20m
    €45–75

  3. Drive  534.7 km

    1. Drive from Karlsruhe to Lyoncar car 534.7 km
    5h 27m
    €101–145

  4. Train to Strasbourg International Airport, fly

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    4h 2m
    €130–357

  5. Train via Lyon Part Dieu

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    5h 55m
    €103–178

  6. Train, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Lausannetrain train
    3. Take the bus from Lausanne Bus Station to Lyon Perrache Bus Stationbus bus
    9h 23m
    €94–220

  7. Train to Frankfurt, fly

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    5h 15m
    €148–380

  8. Train to Stuttgart Airport, fly

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Lyon–Saint Exupéry Airport (LYS)plane plane STR - LYS
    7h 50m
    €137–335

Karlsruhe to Lyon by train

Calendar1Weekly Trains
Duration5h 48mAverage Duration
Ticket€113Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Lyon.ExpandLaunch map view
  • Distance: 591.7 km
  • Duration: 5h 48m

What companies run services between Karlsruhe, Germany and Lyon, France?

You can take a train from Karlsruhe Hauptbahnhof to Lyon Perrache via Strasbourg Bahnhof and Strasbourg in around 5h 48m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Lyon every 4 hours. Tickets cost €50–75 and the journey takes 8h 20m. BlaBlaCar Bus also services this route 3 times a day.

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