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How to get fromKarlsruhe to Madridby train, plane, train (TGV, Renfe, Ouigo), bus, or car

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There are 10 ways to get from Karlsruhe to Madrid by train, plane, train (TGV, Renfe, Ouigo), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FRA - MAD
    6h 14m
    €105–324
  2. Fly from Karlsruhe/Baden-Baden Airport

    cheapest
    1. Fly from Karlsruhe/Baden-Baden Airport (FKB) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FKB - MAD
    8h 6m
    €90–260
  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    3. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    4. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    14h 42m
    €250–533
  4. Bus

    1. Take the bus from Karlsruhe - Central Station South Side to Estación Sur de Autobusesbus bus BlaBlaCar Bus
    26h 50m
    €170–300
  5. Drive 1,667.6 km

    1. Drive from Karlsruhe to Madridcar car 1,667.6 km
    16h 14m
    €265–382
  6. Train to Basel, fly

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Fly from Basel (BSL) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane BSL - MAD
    6h 55m
    €91–366
  7. Train to Strasbourg International Airport, fly

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane SXB - MAD
    5h 47m
    €112–319
  8. Train, train to Zurich Airport, fly

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane ZRH - MAD
    8h 10m
    €136–473
  9. Train, train to Luxembourg, fly

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Take the train from Strasbourg to Luxembourgtrain train
    3. Fly from Luxembourg (LUX) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane LUX - MAD
    8h 32m
    €111–356
  10. Train, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 20 / ...
    2. Take the bus from Mannheim central bus station to Valladolidbus bus
    3. Take the bus from Valladolid to Madrid Moncloabus bus
    30h 1m
    €167–309

Karlsruhe to Madrid by train

Calendar14Weekly Trains
Duration14h 42mAverage Duration
Ticket€250Cheapest Price
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Questions & Answers

What companies run services between Karlsruhe, Germany and Madrid, Spain?

You can take a train from Karlsruhe Hauptbahnhof to Madrid-Puerta de Atocha-Almudena Grandes via Strasbourg Bahnhof, Strasbourg, Lyon Part Dieu, and Barcelona-Sants in around 14h 42m. Alternatively, BlaBlaCar Bus operates a bus from Karlsruhe - Central Station South Side to Estación Sur de Autobuses twice daily. Tickets cost €170–300 and the journey takes 26h 50m.

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