There are 6 ways to get from Karlsruhe to Mainz, Hauptbahnhof by train, bus, car, or rideshare
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Mannheim
best- Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain 20 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain 55 / ...
1h 17m€23–102Rideshare
cheapest- Take the rideshare from Karlsruhe to Mainz139.1 km
1h 54m€5–10Bus via Frankfurt Airport
- Take the bus from Karlsruhe central train station to Frankfurt Airportbus FlixBus 108 / ...
- Take the bus from Frankfurt to Mainz, Hbf West/Taubertsbergb.bus S8x / ...
3h 30m€18–30Drive 140.5 km
- Drive from Karlsruhe to Mainz, Hauptbahnhofcar 140.5 km
1h 17m€20–29Train
- Take the train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhoftrain Re4
1h 41m€23–110Bus
- Take the bus from Karlsruhe central train station to Mainz central train stationbus FlixBus 476
3h 50m€15–27
Karlsruhe to Mainz, Hauptbahnhof by train
Questions & Answers
The cheapest way to get from Karlsruhe to Mainz, Hauptbahnhof is to rideshare which costs €5 - €10 and takes 1h 54m.
The fastest way to get from Karlsruhe to Mainz, Hauptbahnhof is to train via Mannheim which takes 1h 17m and costs €22 - €110.
Yes, there is a direct bus departing from Karlsruhe central train station station and arriving at Mainz central train station station. Services depart twice daily, and operate every day. The journey takes approximately 3h 50m.
Yes, there is a direct train departing from Karlsruhe Hauptbahnhof and arriving at Mainz, Hauptbahnhof. Services depart hourly, and operate every day. The journey takes approximately 1h 41m.
The distance between Karlsruhe and Mainz, Hauptbahnhof is 130 km. The road distance is 140.5 km.
The best way to get from Karlsruhe to Mainz, Hauptbahnhof without a car is to train via Mannheim which takes 1h 17m and costs €22 - €110.
It takes approximately 1h 17m to get from Karlsruhe to Mainz, Hauptbahnhof, including transfers.
Karlsruhe to Mainz, Hauptbahnhof bus services, operated by FlixBus, depart from Karlsruhe central train station.
Karlsruhe to Mainz, Hauptbahnhof train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Mainz, Hauptbahnhof is to train via Mannheim which takes 1h 17m and costs €22 - €110. Alternatively, you can bus via Frankfurt Airport, which costs €18 - €35 and takes 3h 30m.
What companies run services between Karlsruhe, Germany and Mainz, Hauptbahnhof, Germany?
You can take a train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof via Mannheim, Hauptbahnhof in around 1h 17m. Alternatively, you can take a bus from Karlsruhe central train station to Mainz, Hbf West/Taubertsbergb. via Frankfurt Airport and Frankfurt in around 3h 30m.
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €10–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €12–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 2h 23m
- Frequency
- 3 times a day
- Estimated price
- €25–110
- Website
- Deutsche Bahn Intercity (DB IC)
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- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Every 30 minutes
- Estimated price
- €14–26
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €17–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 2h 25m
- Frequency
- Every 4 hours
- Estimated price
- €30–60
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Schedules at
- Süwex
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Karlsruhe central train station to Frankfurt Airport
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- €13–22
- Website
- Flixbus
Bus from Karlsruhe central train station to Mainz central train station
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- €15–27
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Karlsruhe central train station to Frankfurt Airport
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €13–24
- Website
- BlaBlaCar Bus
- Phone
- +49 30 311682904
- Website
- DB Bus
Bus from Frankfurt to Mainz, Hbf West/Taubertsbergb.
- Ave. Duration
- 58 min
- Frequency
- Every 20 minutes
- Estimated price
- €5–7
- Website
- DB Bus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Karlsruhe to Mainz
- Ave. Duration
- 1h 42m
- Frequency
- 3 times a day
- Estimated price
- €5–10
- Schedules at
- BlaBlaCar
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More Questions & Answers
Karlsruhe to Mainz, Hauptbahnhof bus services, operated by FlixBus, arrive at Mainz central train station.
Karlsruhe to Mainz, Hauptbahnhof train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Karlsruhe to Mainz, Hauptbahnhof is 141 km. It takes approximately 1h 17m to drive from Karlsruhe to Mainz, Hauptbahnhof.
Book your Karlsruhe to Mainz, Hauptbahnhof train tickets online with Omio.
Book your Karlsruhe to Mainz, Hauptbahnhof bus tickets online with Omio and FlixBus.
There are 1220+ hotels available in Mainz, Hauptbahnhof.
Check out Blablacar's carpooling service for rideshare options between Karlsruhe and Mainz, Hauptbahnhof. A great option if you don't have a driver's licence or want to avoid public transport.