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There are 12 ways to get from Karlsruhe to Milan by train, bus, night train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Recommended option

Train  •  6h 59m

  1. Take the train from Karlsruhe Hauptbahnhof to Basel SBB 43 / ...
  2. Take the train from Basel SBB to Milano Centrale Station 85

Cheapest option

Bus  •  8h 10m

  1. Take the bus from Karlsruhe central train station to Milano, Autostazione Lampugnano 476 / ...

10 alternative options

Night train, train  •  8h 56m

  1. Take the night train from Karlsruhe Hauptbahnhof to Zürich hbf 12 / ...
  2. Take the train from Zürich Hb to Chiasso Ec / ...
  3. Take the train from Chiasso to Milano Centrale Ec / ...

Train via Singen  •  9h 39m

  1. Take the train from Karlsruhe Hauptbahnhof to Singen Re2 / ...
  2. Take the train from Singen to Zürich Hb Ic
  3. Take the train from Zuerich Hb to Milano Centrale Ec

Drive  •  5h 13m

  1. Drive from Karlsruhe to Milan 531.4 km

Train to Stuttgart, fly to Milan Linate  •  4h 43m

  1. Take the train from Karlsruhe Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Milan Linate (LIN) STR - LIN

Train to Frankfurt, fly to Milan Linate  •  4h 30m

  1. Take the train from Karlsruhe Hauptbahnhof to Frankfurt
  2. Fly from Frankfurt (FRA) to Milan Linate (LIN) FRA - LIN

Train to Stuttgart, fly to Milan Malpensa  •  5h 25m

  1. Take the train from Karlsruhe Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Milan Malpensa (MXP) STR - MXP

Train to Frankfurt, fly to Milan Malpensa  •  5h 17m

  1. Take the train from Karlsruhe Hauptbahnhof to Frankfurt
  2. Fly from Frankfurt (FRA) to Milan Malpensa (MXP) FRA - MXP

Train to Karlsruhe/Baden Baden, fly to Milan Bergamo  •  5h 8m

  1. Take the train from Karlsruhe Hauptbahnhof to Rastatt
  2. Fly from Karlsruhe/Baden Baden (FKB) to Milan Bergamo (BGY) FKB - BGY

Train, train to Zurich, fly to Milan Malpensa  •  6h 17m

  1. Take the train from Karlsruhe Hauptbahnhof to Basel SBB
  2. Take the train from Basel Sbb to Zürich Hb
  3. Fly from Zurich (ZRH) to Milan Malpensa (MXP) ZRH - MXP

Train to Stuttgart, fly to Zurich, train  •  7h 21m

  1. Take the train from Karlsruhe Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Zurich (ZRH) STR - ZRH
  3. Take the train from Zürich Hb to Lugano
  4. Take the train from Lugano to Milano Centrale

Karlsruhe to Milan by train

6 Weekly Trains
6h 59m Average Duration
€139 Cheapest Price
See schedules

Questions & Answers

The cheapest way to get from Karlsruhe to Milan is to bus which costs €35 - €60 and takes 8h 10m.

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The fastest way to get from Karlsruhe to Milan is to train and fly which takes 4h 30m and costs €120 - €360.

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Yes, there is a direct bus departing from Karlsruhe central train station station and arriving at Milano, Autostazione Lampugnano. Services depart five times a day, and operate every day. The journey takes approximately 8h 10m.

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No, there is no direct train from Karlsruhe to Milan station. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Milano Centrale Station via Basel SBB. The journey, including transfers, takes approximately 6h 59m.

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The distance between Karlsruhe and Milan is 559 km. The road distance is 531.4 km.

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The best way to get from Karlsruhe to Milan without a car is to train which takes 6h 59m and costs €130 - €250.

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It takes approximately 6h 59m to get from Karlsruhe to Milan, including transfers.

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Karlsruhe to Milan bus services, operated by FlixBus, depart from Karlsruhe central train station.

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Karlsruhe to Milan train services, operated by Deutsche Bahn Intercity-Express, depart from Karlsruhe Hauptbahnhof station.

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The best way to get from Karlsruhe to Milan is to train which takes 6h 59m and costs €130 - €250. Alternatively, you can bus, which costs €35 - €60 and takes 8h 10m.

Mode details

Map of how to get from Karlsruhe to Milan.
Launch map view
  • Distance: 559.5 km
  • Duration: 6h 59m

What companies run services between Karlsruhe, Germany and Milan, Italy?

You can take a train from Karlsruhe to Milano Centrale via Basel SBB in around 6h 59m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Milano, Autostazione Lampugnano 4 times a day. Tickets cost €40 - €60 and the journey takes 8h 10m. BlaBlaCar Bus also services this route 4 times a week.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Milan Linate
Ave. Duration
1h 10m
When
Every day
Estimated price
€130 - €600
Flights from Stuttgart to Milan Malpensa via Frankfurt
Ave. Duration
3h 7m
When
Every day
Estimated price
€130 - €430
Flights from Stuttgart to Milan Malpensa via Munich
Ave. Duration
3h
When
Every day
Estimated price
€120 - €390
Flights from Frankfurt to Milan Malpensa
Ave. Duration
1h 15m
When
Every day
Estimated price
€110 - €550
Flights from Frankfurt to Milan Malpensa via Munich
Ave. Duration
3h 7m
When
Every day
Estimated price
€110 - €550
Swiss
Website
swiss.com
Flights from Frankfurt to Milan Malpensa via Zurich
Ave. Duration
3h 20m
When
Every day
Estimated price
€130 - €700
Flights from Zurich to Milan Malpensa
Ave. Duration
55 min
When
Every day
Estimated price
€140 - €650
Flights from Stuttgart to Zurich
Ave. Duration
45 min
When
Every day
Estimated price
€170 - €800
Air Dolomiti
Website
airdolomiti.it
Flights from Frankfurt to Milan Linate
Ave. Duration
1h 10m
When
Every day
Estimated price
€130 - €650
Flights from Frankfurt to Milan Malpensa
Ave. Duration
1h 15m
When
Every day
Estimated price
€110 - €370
Alitalia
Website
alitalia.com
Flights from Stuttgart to Milan Linate
Ave. Duration
1h 5m
When
Every day
Estimated price
€70 - €300
Flights from Frankfurt to Milan Linate
Ave. Duration
1h 15m
When
Every day
Estimated price
€95 - €430
Eurowings
Website
eurowings.com
Flights from Stuttgart to Milan Malpensa
Ave. Duration
1h 5m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
€65 - €360
Ethiopian Airlines
Website
ethiopianairlines.com
Flights from Frankfurt to Milan Malpensa
Ave. Duration
1h 15m
When
Every day
Estimated price
€110 - €650
Flights from Zurich to Milan Malpensa
Ave. Duration
1h 10m
When
Monday, Wednesday, Friday, Saturday and Sunday
Estimated price
€130 - €420
Ryanair
Website
ryanair.com
Flights from Karlsruhe/Baden Baden to Milan Bergamo
Ave. Duration
1h 5m
When
Monday, Wednesday, Thursday and Sunday
Estimated price
€29 - €410
Train operators
Deutsche Bahn Intercity-Express

German rail company Deutsche Bahn is known for its efficient and comfortable service. It offers many different types of rail transportation, including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare (bookings usually open 6 months in advance for domestic tickets).

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Karlsruhe Hauptbahnhof to Basel SBB
Ave. Duration
1h 47m
Frequency
Hourly
Estimated price
€41 - €46
Website
https://www.bahn.com/en
Night train from Karlsruhe Hauptbahnhof to Zürich hbf
Ave. Duration
3h 56m
Frequency
3 times a week
Estimated price
€50 - €60
Website
https://www.bahn.com/en
Train from Karlsruhe Hauptbahnhof to Singen
Ave. Duration
2h 49m
Frequency
Once daily
Estimated price
€43 - €49
Website
https://www.bahn.com/en
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration
56 min
Frequency
Hourly
Estimated price
€27 - €31
Website
https://www.bahn.com/en
Train from Karlsruhe Hauptbahnhof to Frankfurt
Ave. Duration
1h 6m
Frequency
Every 4 hours
Estimated price
€34 - €38
Website
https://www.bahn.com/en
Train from Karlsruhe Hauptbahnhof to Rastatt
Ave. Duration
11 min
Frequency
Twice daily
Estimated price
€20 - €23
Website
https://www.bahn.com/en
Deutsche Bahn Regional

Deutsche Bahn’s regional network is made up of IRE (Interregio-Express), RE (Regional-Express), RB (Regionalbahn) and S-Bahn trains. Ticket prices are fixed and there’s no seat reservations – just turn up, buy a ticket and jump on the next train. All regional trains depart regularly and connect to local and long-distance services.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Karlsruhe Hauptbahnhof to Basel SBB
Ave. Duration
2h 40m
Frequency
5 times a week
Estimated price
€28 - €40
Website
https://www.bahn.com/en
Train from Karlsruhe Hauptbahnhof to Singen
Ave. Duration
2h 43m
Frequency
Hourly
Estimated price
€30 - €45
Website
https://www.bahn.com/en
Train from Karlsruhe Hauptbahnhof to Rastatt
Ave. Duration
22 min
Frequency
Every 20 minutes
Estimated price
€8 - €12
Website
https://www.bahn.com/en
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs.

Contact Details
Phone
+41 848 44 66 88
Website
sbb.ch
Train from Basel SBB to Milano Centrale Station
Ave. Duration
4h 12m
Frequency
6 times a week
Estimated price
€110 - €200
Website
https://www.sbb.ch/en
Train from Zürich Hb to Chiasso
Ave. Duration
3h 22m
Frequency
Hourly
Estimated price
€65 - €120
Website
https://www.sbb.ch/en
Train from Chiasso to Milano Centrale
Ave. Duration
46 min
Frequency
Hourly
Estimated price
€14 - €26
Website
https://www.sbb.ch/en
Train from Singen to Zürich Hb
Ave. Duration
54 min
Frequency
Hourly
Estimated price
€26 - €50
Website
https://www.sbb.ch/en
Train from Zuerich Hb to Milano Centrale
Ave. Duration
4h 17m
Frequency
Every 4 hours
Estimated price
€70 - €130
Website
https://www.sbb.ch/en
Train from Basel Sbb to Zürich Hb
Ave. Duration
1h 13m
Frequency
Every 15 minutes
Estimated price
€30 - €60
Website
https://www.sbb.ch/en
Train from Zürich Hb to Lugano
Ave. Duration
1h 55m
Frequency
Every 30 minutes
Estimated price
€55 - €110
Website
https://www.sbb.ch/en
Train from Lugano to Milano Centrale
Ave. Duration
1h 15m
Frequency
Hourly
Estimated price
€22 - €40
Website
https://www.sbb.ch/en
Go Ahead BW
Phone
+49 711 400 534 44
Website
go-ahead-bw.de
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
53 min
Frequency
Every 30 minutes
Estimated price
€14 - €27
Website
Go Ahead BW
2nd Class Ticket
€14 - €18
1st Class Ticket
€18 - €27
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
+33 1 84 94 36 35
Website
en.oui.sncf
Train from Karlsruhe Hbf to Stuttgart Hbf
Ave. Duration
37 min
Frequency
3 times a day
Estimated price
€21 - €50
Website
https://www.sncf.com/en
2nd Class
€21 - €28
1st Class
€35 - €50
Sweg
Phone
07821/9960770
Email
info@sweg.de
Website
sweg.de
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration
1h 36m
Frequency
5 times a week
Schedules at
sweg.de
Albtal-Verkehrs-Gesellschaft mbH
Phone
+49 721 61075885
Email
info@avg.karlsruhe.de
Website
avg.info
Train from Karlsruhe Bahnhofsvorplatz to Rastatt
Ave. Duration
25 min
Frequency
Every 30 minutes
Website
Albtal-Verkehrs-Gesellschaft mbH
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2Rio's guide to FlixBus
Contact Details
Phone
+49 30 300 137 300
Email
service@flixbus.com
Website
flixbus.de
Bus from Karlsruhe central train station to Milano, Autostazione Lampugnano
Ave. Duration
8h 10m
Frequency
4 times a day
Estimated price
€40 - €60
Website
https://www.flixbus.co.uk
Frequently asked questions
Is there Wi-Fi on FlixBus?
Yes - FlixBus offers free Wi-Fi
Are there power outlets on FlixBus?
Yes
Does FlixBus offer meals or snacks?
Yes - snacks and drinks may be purchased from the driver. Please note, this is not available on all services.
For more information, please visit this page
BlaBlaCar Bus

As the bus subsidiary of French railway SNCF, Ouibus offers eco-friendly coaches serving 35 French cities and 10 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
+33 1 71 53 01 80
Website
blablacar.fr
Bus from Karlsruhe to Milano, Autostazione Lampugnano
Ave. Duration
9h 20m
Frequency
4 times a week
Estimated price
€35 - €55
Website
https://www.blablacar.co.uk/

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Karlsruhe to Milan bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.

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Karlsruhe to Milan train services, operated by Swiss Railways (SBB/CFF/FFS), arrive at Milano Centrale Station.

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Yes, the driving distance between Karlsruhe to Milan is 531 km. It takes approximately 5h 13m to drive from Karlsruhe to Milan.

Get driving directions

Book your Karlsruhe to Milan bus tickets online with FlixBus and Omio.

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