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How to get fromKarlsruhe to Milanby train, bus, night train, car, or plane

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There are 10 ways to get from Karlsruhe to Milan by train, bus, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    7h 41m
    €69–477

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Milano, Autostazione Lampugnanobus bus N77
    8h 55m
    €40–75

  3. Night train, bus

    1. Take the nighttrain from Karlsruhe Hbf to Zuerich Hbnighttrain night train Nj
    2. Take the bus from Zürich to Milano, Autostazione Lampugnanobus bus BlaBlaCar Bus
    8h 45m
    €48–133

  4. Drive  528.4 km

    1. Drive from Karlsruhe to Milancar car 528.4 km
    5h 14m
    €84–121

  5. Train via Singen

    1. Take the train from Karlsruhe Hauptbahnhof to Singentrain train Re2
    2. Take the train from Singen to Zürich HBtrain train Ic
    3. Take the train from Zürich HB to Como S. Giovannitrain train Ec
    4. Take the train from Como S.Giovanni to Milano Porta Garibalditrain train S11
    9h 7m
    €135–479

  6. Train, train to Frankfurt, fly to Milan Linate Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    4h 38m
    €55–240

  7. Train to Stuttgart Airport, fly to Milano Malpensa Airport, train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane plane STR - MXP
    3. Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain train
    5h 34m
    €87–239

  8. Train, train to Frankfurt, fly to Milano Malpensa Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    4. Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain train
    5h 17m
    €78–283

  9. Train, train to Zurich Airport, fly to Milano Malpensa Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Milano Malpensa Airport (MXP)plane plane ZRH - MXP
    4. Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain train
    6h 24m
    €129–434

  10. Train, train to Luxembourg, fly to Milan Linate Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Take the train from Strasbourg to Luxembourgtrain train
    3. Fly from Luxembourg (LUX) to Milan Linate Airport (LIN)plane plane LUX - LIN
    7h 17m
    €106–396

Karlsruhe to Milan by train

Calendar76Weekly Trains
Duration7h 41mAverage Duration
Ticket€69Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Milan.ExpandLaunch map view
  • Distance: 522.1 km
  • Duration: 7h 41m

What companies run services between Karlsruhe, Germany and Milan, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Milano Centrale via Basel SBB and Lugano in around 7h 41m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Milano, Autostazione Lampugnano once daily. Tickets cost €40–75 and the journey takes 8h 55m.

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