There are 8 ways to get from Karlsruhe to Milano Centrale Station by train, bus, car, plane, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
7h 40m€69–506Bus
cheapest- Take the bus from Karlsruhe central train station to Milanbus FlixBus N487 / ...
8h€47–78Drive 528.4 km
- Drive from Karlsruhe to Milano Centrale Stationcar 528.4 km
5h 13m€82–119Train to Frankfurt, fly to Milan Linate Airport
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
4h 54m€66–248Night train, train
- Take the nighttrain from Karlsruhe Hbf to Zuerich Hbnighttrain Nj
- Take the train from Zürich HB to Cadenazzotrain
- Take the train from Cadenazzo to Milano Centraletrain
10h 37m€87–187Train to Frankfurt, fly to Milano Malpensa Airport, train
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane FRA - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Centraletrain
5h 24m€83–289Train to Stuttgart Airport, fly to Milano Malpensa Airport, train
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane STR - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Centraletrain
5h 38m€87–245Train, train to Zurich Airport, fly to Milano Malpensa Airport
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Milano Malpensa Airport (MXP)plane ZRH - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Centraletrain
6h 35m€124–433
Karlsruhe to Milano Centrale Station by train
Questions & Answers
The cheapest way to get from Karlsruhe to Milano Centrale Station is to bus which costs €45 - €80 and takes 8h.
The fastest way to get from Karlsruhe to Milano Centrale Station is to train and fly which takes 4h 54m and costs €65 - €250.
No, there is no direct bus from Karlsruhe station to Milano Centrale Station. However, there are services departing from Karlsruhe central train station and arriving at stazione centrale via tonale via lotto m1 m5. The journey, including transfers, takes approximately 8h.
No, there is no direct train from Karlsruhe to Milano Centrale Station. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Milano Centrale via Basel SBB and Lugano. The journey, including transfers, takes approximately 7h 40m.
The distance between Karlsruhe and Milano Centrale Station is 522 km. The road distance is 528.4 km.
The best way to get from Karlsruhe to Milano Centrale Station without a car is to train which takes 7h 40m and costs €65 - €550.
It takes approximately 7h 40m to get from Karlsruhe to Milano Centrale Station, including transfers.
Karlsruhe to Milano Centrale Station bus services, operated by FlixBus, depart from Karlsruhe central train station.
Karlsruhe to Milano Centrale Station train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Milano Centrale Station is to train which takes 7h 40m and costs €65 - €550. Alternatively, you can bus, which costs €45 - €80 and takes 8h.
What companies run services between Karlsruhe, Germany and Milano Centrale Station, Italy?
You can take a train from Karlsruhe Hauptbahnhof to Milano Centrale via Basel SBB and Lugano in around 7h 40m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Milan 5 times a day. Tickets cost €40–75 and the journey takes 7h 20m.
- Website
- lufthansa.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–490
Flights from Frankfurt to Milan Linate Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €50–190
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €70–400
Flights from Frankfurt to Milano Malpensa Airport via Munich
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- €110–420
Flights from Stuttgart Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €120–440
- Website
- airdolomiti.it
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–490
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €100–400
- Website
- swiss.com
Flights from Frankfurt to Milano Malpensa Airport via Zurich Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €75–250
Flights from Zurich Airport to Milano Malpensa Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €70–330
- Website
- condor.com
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €50–170
- Website
- easyjet.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €35–130
- Website
- ethiopianairlines.com
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €70–180
Flights from Zurich Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €95–160
- Website
- eurowings.com
Flights from Stuttgart Airport to Milano Malpensa Airport
- Ave. Duration
- 1h
- When
- Monday and Friday
- Estimated price
- €80–160
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–160
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- €23–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- €23–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €35–160
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Once daily
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Once daily
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €85–270
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €27–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–95
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Karlsruhe Hbf to Zuerich Hb
- Ave. Duration
- 4h 1m
- Frequency
- Twice daily
- Estimated price
- €24–93
- Website
- Nightjet
- Sleeper Carriage
- €88–93
- Couchette Carriage
- €55–65
- Seating Carriage
- €24–29
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Zürich HB to Cadenazzo
- Ave. Duration
- 3h 7m
- Frequency
- Every 4 hours
- Estimated price
- €55–85
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Cadenazzo to Milano Centrale
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €7–9
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Milano Centrale
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Milano Centrale
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Milano Centrale
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–26
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–17
- 1st Class Ticket
- €18–26
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 4 hours
- Estimated price
- €16–26
- Website
- TGV inOui
- Phone
- +49 711 2092-7087
- Website
- DB Regio Stuttgart
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 34m
- Frequency
- 5 times a week
- Estimated price
- €14–21
- Schedules at
- DB Regio Stuttgart
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Karlsruhe central train station to Milan
- Ave. Duration
- 7h 20m
- Frequency
- 5 times a day
- Estimated price
- €40–75
- Website
- Flixbus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
More Questions & Answers
Karlsruhe to Milano Centrale Station bus services, operated by FlixBus, arrive at Milan station.
Karlsruhe to Milano Centrale Station train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Karlsruhe to Milano Centrale Station is 528 km. It takes approximately 5h 13m to drive from Karlsruhe to Milano Centrale Station.
Book your Karlsruhe to Milano Centrale Station train tickets online with Omio.
There are 14404+ hotels available in Milano Centrale Station.
















































