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How to get fromKarlsruhe to Pisaby train, plane, train (Trenitalia), bus, or car

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There are 10 ways to get from Karlsruhe to Pisa by train, plane, train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, train to Frankfurt, fly to Pisa International Airport

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    4h 50m
    €118–337

  2. Bus via Milan Bergamo Airport (BGY)

    cheapest
    1. Take the bus from Karlsruhe central train station to Bergamobus bus FlixBus 024
    2. Take the bus from Bergamo to Pisabus bus N1508
    19h 45m
    €86–141

  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Pisa Centraletrain train Re
    11h 47m
    €108–576

  4. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Pisabus bus 443 / ...
    13h 52m
    €121–167

  5. Drive  808.1 km

    1. Drive from Karlsruhe to Pisacar car 808.1 km
    8h 3m
    €128–184

  6. Train to Stuttgart Airport, fly to Florence Peretola Airport, train

    1. Take the train from Karlsruhe Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Florence Peretola Airport (FLR)plane plane STR - FLR
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    8h 28m
    €128–369

  7. Train, train to Frankfurt, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    4. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    6h 52m
    €149–384

  8. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    7h 23m
    €137–378

  9. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    8h 33m
    €166–514

  10. Train via Singen

    1. Take the train from Karlsruhe Hauptbahnhof to Singentrain train Re2
    2. Take the train from Singen to Zürich HBtrain train Ic
    3. Take the train from Zürich HB to Chiassotrain train Ec / ...
    4. Take the train from Chiasso to Pisa Centraletrain train Ec
    14h 21m
    €250–788

Karlsruhe to Pisa by train

Calendar76Weekly Trains
Duration11h 47mAverage Duration
Ticket€108Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Pisa.ExpandLaunch map view
  • Distance: 851.7 km
  • Duration: 4h 50m

What companies run services between Karlsruhe, Germany and Pisa, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Pisa Centrale via Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 11h 47m. Alternatively, you can take a bus from Karlsruhe Central Bus Station to Pisa via Florence Villa Constanza Bus Station in around 13h 52m.

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